“Never Trust to General Impressions, My Boy, but Concentrate Yourself upon Details”: An Unusual and Challenging Presentation of Pheochromocytoma
Open Access
- 15 June 2021
- journal article
- case report
- Published by MDPI AG in Journal of Cardiovascular Development and Disease
- Vol. 8 (6), 71
- https://doi.org/10.3390/jcdd8060071
Abstract
We present the case of a 45-year-old woman admitted to our unit with acute heart failure and cardiogenic shock, requiring an intra-aortic balloon pump insertion and inotropes and vasopressors infusion. Despite such treatment, the patient developed multi organ failure and intravascular disseminated coagulation with haemolysis. The initial diagnosis of acute myocarditis was subsequently denied by the finding of bilateral adrenal masses by MRI scan, and urine and plasma metanephrines measurements confirmed a pheochromocytoma (PCC). Genetic analysis revealed a mutation in the neurofibromatosis type 1 (NF1) gene, and an accurate physical examination drew attention to small cafè-au-lait spots, usually associated with this syndrome. PCC diagnosis should be promptly considered in patients presenting with unexplained acute heart failure and cardiogenic shock of unknown origin, considering its life-threatening complications and the good prognosis after radical surgery.Keywords
This publication has 10 references indexed in Scilit:
- Management of fulminant myocarditis: A diagnosis in search of its etiology but with therapeutic optionsCurrent Heart Failure Reports, 2014
- Pheochromocytoma Presenting as Acute Heart Failure Leading to Cardiogenic Shock and Multiorgan FailureCase Reports in Medicine, 2011
- Cardiogenic shock with basal transient left ventricular ballooning (Takotsubo-like cardiomyopathy) as first presentation of pheochromocytomaJournal of Cardiovascular Medicine, 2010
- Sepsis and Cardiomyopathy as Rare Clinical Manifestations of Pheochromocytoma – Two Case Report StudiesExperimental and Clinical Endocrinology & Diabetes, 2010
- [Cardiomyopathy: first clinical manifestation of a pheochromocytoma--case report].2010
- Pheochromocytoma crisis presenting with shock and tako-tsubo-like cardiomyopathyInternational Journal of Cardiology, 2009
- Rapidly Reversible Cardiogenic Shock as a Pheochromocytoma PresentationThe American Journal of Medicine, 2007
- Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recoveryEuropean Heart Journal, 2007
- Guidelines for the diagnosis and management of individuals with neurofibromatosis 1Journal of Medical Genetics, 2006
- Clinical and Genetic Characteristics of Patients with Neurofibromatosis Type 1 and PheochromocytomaThe New England Journal of Medicine, 2006