PredyCLU: A prediction system for chronic leg ulcers based on fuzzy logic; part II—Exploring the arterial side
- 13 April 2020
- journal article
- research article
- Published by Wiley in International Wound Journal
- Vol. 17 (4), 987-991
- https://doi.org/10.1111/iwj.13360
Abstract
Peripheral arterial disease (PAD) and its most severe form, critical limb ischaemia (CLI), are very common clinical conditions related to atherosclerosis and represent the major causes of morbidity, mortality, disability, and reduced quality of life (QoL), especially for the onset of ischaemic chronic leg ulcers (ICLUs) and the subsequent need of amputation in affected patients. Early identification of patients at risk of developing ICLUs may represent the best form of prevention and appropriate management. In this study, we used a Prediction System for Chronic Leg Ulcers (PredyCLU) based on fuzzy logic applied to patients with PAD. The patient population consisted of 80 patients with PAD, of which 40 patients (30 males [75%] and 10 females [25%]; mean age 66.18 years; median age 67.50 years) had ICLUs and represented the case group. Forty patients (100%) (27 males [67.50%] and 13 females [32.50%]; mean age 66.43 years; median age 66.50 years) did not have ICLUs and represented the control group. In patients of the case group, the higher was the risk calculated with the PredyCLU the more severe were the clinical manifestations recorded. In this study, the PredyCLU algorithm was retrospectively applied on a multicentre population of 80 patients with PAD. The PredyCLU algorithm provided a reliable risk score for the risk of ICLUs in patients with PAD.Keywords
This publication has 11 references indexed in Scilit:
- Peripheral artery disease: epidemiology and global perspectivesNature Reviews Cardiology, 2016
- Current accepted hemodynamic criteria for critical limb ischemia do not accurately stratify patients at high risk for limb lossJournal of Vascular Surgery, 2016
- PredyCLU: a prediction system for chronic leg ulcers based on fuzzy logic; part I – exploring the venous sideInternational Wound Journal, 2015
- The need for improved risk stratification in chronic critical limb ischemiaJournal of Vascular Surgery, 2014
- Epidemiology of peripheral arterial disease and critical limb ischemia in an insured national populationJournal of Vascular Surgery, 2014
- Peripheral arterial disease: A growing problem for the internistEuropean Journal of Internal Medicine, 2009
- Risk Factors for Progression of Peripheral Arterial Disease in Large and Small VesselsCirculation, 2006
- ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): Executive Summary A Collaborative Report From the American Association for Vascular Surgery/Society for Vascular Surgery,Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease FoundationJournal of the American College of Cardiology, 2006
- Prevalence, risk factors and cardiovascular comorbidity of symptomatic peripheral arterial disease in ItalyAtherosclerosis, 2004
- Recommended standards for reports dealing with lower extremity ischemia: Revised versionJournal of Vascular Surgery, 1997