The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2
Open Access
- 1 July 2020
- journal article
- editorial
- Published by American Association for Cancer Research (AACR) in Cancer Discovery
- Vol. 10 (7), 916-921
- https://doi.org/10.1158/2159-8290.CD-20-0559
Abstract
The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.Other Versions
Funding Information
- NIH (P50AI150476, U19AI135990, U19AI135972, R01AI143292, R01AI120694, P01A1063302, R01AI122747, U54CA209891)
- NIH (F32CA239336)
- NIH (F32CA239333)
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