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Journal POJ Clinical Case Reports

7 articles
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Published: 12 October 2018
POJ Clinical Case Reports; doi:10.32648/2639-3298

Samar Alwafi, Razan Alluhaibi, Sahar Alsharif, Bader Alomair
Published: 31 August 2018
POJ Clinical Case Reports, Volume 1, pp 1-4; doi:10.32648/2639-3298/1/1/005

Abstract:Sarcoidosis is a potentially fatal systemic inflammatory granulomatous disease, can occur in adult and pediatric patients, but it is relatively rare in children. Juvenile sarcoidosis has a diverse clinical course depending on the age of onset. Bone involvement is rarely noted in children with sarcoidosis and usually seen late in the course of the disease and is rarely the initial manifestation. Here we report a case of early onset juvenile sarcoidosis revealed by cutaneous and osseous lytic lesions of the phalanges. Keywords: Atypical, Early onset, Juvenile, Sarcoidosis, Osteolytic lesions, Osseous sarcoidosis, Phalanges.
Published: 31 August 2018
POJ Clinical Case Reports, Volume 1; doi:10.32648/2639-3298/1/1

Koji Ebe, Hiroshi Bando, Tetsuo Muneta, Masahiro Bando, Yoshikazu Yonei
POJ Clinical Case Reports, Volume 1, pp 1-7; doi:10.32648/2639-3298/1/1/004

Abstract:Background: Low Carbohydrate Diet (LCD) and Calorie Restriction (CR) have been on discussion for years. Authors have continued diabetic research about LCD, CR, Morbus (M) value and insulin secretion. In this study, homeostasis model assessment (HOMA) was investigated. Subjects and Methods: Subjects enrolled were 52 patients with type 2 diabetes mellitus (T2DM) (average 62.3 years). Methods included the measurement of fasting glucose and immunoreactive insulin (IRI), daily profile of blood glucose and M value. Results: The obtained data were as follows: average HbA1c 8.0%, average glucose of daily profile 222 mg/dL. Median data were M value 151, HOMA-R 1.07, HOMA-β 11.1. Divided into 4 groups due to M value, the levels of HOMA-R and HOMA-β in each group were 0.68, 1.08, 1.64, 1.38 and 16.9, 16.3, 10.2, 5.3, respectively. Significant correlation were observed between M value and HOMA-R (p
Charles M. Lepkowsky
POJ Clinical Case Reports, Volume 1, pp 1-4; doi:10.32648/2639-3298/1/1/003

Abstract:In a series of case studies, four patients diagnosed with the α‐synuclein or “Lewy body” disorders Parkinson’s disease (PD) and Neurocognitive Disorder with Lewy Bodies (NCDLB) at different stages of disease progression were treated for the symptoms of constipation, obstipation, and impaction with the acetylcholinesterase inhibitor (AChEI) Donepezil. Initial findings indicated that the use of Donepezil was associated with significant symptom reduction. The symptom status of each of the four patients was reviewed at six and twelve month intervals, with no apparent reduction in bowel motility, nor the emergence of any new symptoms. After eighteen months, the symptom status of each of the four patients was again assessed. Evaluation of the results suggests that the AChEI Donepezil may have long-term benefit for relieving the symptoms of constipation, obstipation and impaction in patients with α‐synuclein disorders. Keywords: Neurocognitive Disorder with Lewy Bodies, Parkinson’s disease, constipation, Donepezil, acetylcholinesterase inhibitor
Bushra Salah Alraddadi, Tahani Magliah, Yasser Al Otaibi
POJ Clinical Case Reports, Volume 1, pp 1-2; doi:10.32648/2639-3298/1/1/002

Abstract:Linear IgA bullous dermatosis (LABD) is rare autoimmune disease that can be caused with or without drugs. We present a 32 year old male with LABD secondary to Amoxicillin-clavulanic acid with complete recovery after the antibiotic was discontinued. Keywords: Linear IgA Bullous disease, Vancomycin, Amoxicillin-clavulanic acid
Arianne Clare Agdamag, Joanne Michelle Gomez
POJ Clinical Case Reports, Volume 1, pp 1-2; doi:10.32648/2639-3298/1/1/001

Abstract:Platypnea orthodeoxia syndrome (POS) is an uncommon phenomenon characterized by dyspnea and arterial desaturation in an upright position improved with recumbency. It is due to an anatomical factor that allows for interatrial communication and a functional factor that promotes right to left shunting. Once identified, early intervention allows for rapid symptomatic improvement. This case highlights that among patients who present with positional hypoxia, POS should be considered as a possible etiology. Thorough evaluation is warranted to identify potentially reversible etiologies and guide management. Keywords: Platypnea orthodeoxia syndrome, Atrial septal defect, Amplatzer closure device
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