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Journal Cytogenetic and Genome Research

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8,703 articles
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Janine E. Deakin, Tariq Ezaz
Published: 16 January 2019
Cytogenetic and Genome Research; doi:10.1159/000495974

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Michael Schmid, Claus Steinlein, Alina M. Reiter, Michail Rovatsos, Marie Altmanová, Sofia Mazzoleni, Martina Johnson Pokorná, Lukáš Kratochvíl
Published: 15 January 2019
Cytogenetic and Genome Research; doi:10.1159/000495893

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Alessio Iannucci, Marie Altmanová, Claudio Ciofi, Malcolm Ferguson-Smith, Jorge C. Pereira, Ivan Rehák, Roscoe Stanyon, Petr Velenský, Michail Rovatsos, Lukáš Kratochvíl, et al.
Published: 15 January 2019
Cytogenetic and Genome Research; doi:10.1159/000496171

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Liang-Liang Fan, Hao Huang, Jie-Yuan Jin, Jing-Jing Li, Ya-Qin Chen, Rong Xiang
Published: 11 January 2019
Cytogenetic and Genome Research; doi:10.1159/000496077

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Alessio Iannucci, Marta Svartman, Massimo Bellavita, Guido Chelazzi, Roscoe Stanyon, Claudio Ciofi
Published: 11 January 2019
Cytogenetic and Genome Research; doi:10.1159/000495833

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Marla C. McPherson, Hans H. Cheng, Justin M. Smith, Mary E. Delany
Published: 21 December 2018
Cytogenetic and Genome Research; doi:10.1159/000495174

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Fernanda T. Bellucco, Rodrigo A. Fock, Hélio R. De Oliveira-Júnior, Ana B. Perez, Maria I. Melaragno
Published: 18 December 2018
Cytogenetic and Genome Research; doi:10.1159/000494682

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Rodolfo Martín-Del-Campo, Itzel Sifuentes-Romero, Alejandra García-Gasca
Published: 15 December 2018
Cytogenetic and Genome Research; doi:10.1159/000495712

Abstract:Reptiles are ancestral organisms presenting a variety of shapes, from the elongated vertebral column of the snake to the turtle dorsalized ribs or retractile neck. Body plans are specified by a conserved group of homeobox-containing genes (Hox genes), which encode transcription factors important in cell fate and vertebral architecture along the anteroposterior axis during embryonic development; thus, dysregulation of these genes may cause congenital malformations, from mild-sublethal to embryonic-lethal. The genetic pool, maternal transfer, and environmental conditions during egg incubation affect development; environmental factors such as temperature, moisture, oxygen, and pollution may alter gene expression by epigenetic mechanisms. Thus, in this review, we present information regarding Hox genes and development in reptiles, including sex determination and teratogenesis. We also present some evidence of epigenetic regulation of Hox genes and the role of the environment in epigenetic modulation of gene expression. So far, the evidence suggests that the molecular instructions encoded by Hox genes to build a snake, a lizard, or a turtle represent the interplay between genome and epigenome after years of evolution, with occasional environmentally induced molecular mistakes leading to abnormal body shapes.
Sarah Correll-Tash, Laura Conlin, Beth A. Mininger, Brenna Lilley, Michael T. Mennuti, Beverly S. Emanuel
Published: 14 December 2018
Cytogenetic and Genome Research; doi:10.1159/000494648

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Martin Knytl, Tereza Tlapakova, Tereza Vankova, Vladimir Krylov
Published: 11 December 2018
Cytogenetic and Genome Research; doi:10.1159/000494708

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