Journal of Pharmaceutical and Health Research

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EISSN : 2721-0715
Total articles ≅ 27
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, Nora Elsaputri, Riska Nadia, Syifa Yulia, Indah Indah, Siti Mulyana, Elvita Meivianthy, Nisaul Fitria, Siti Raihan Utami
Journal of Pharmaceutical and Health Research, Volume 3, pp 15-18; https://doi.org/10.47065/jharma.v3i1.1311

Abstract:
Traditional medicine or herbal medicine is widely used by ordinary people because it is considered safer than the use of modern medicine. This is because traditional medicine has fewer side effects than modern medicine. The purpose of this study was to observe the antipyretic effect of the ethanolic extract of basil leaves on mice. The experimental design in this study used a completely randomized design (CRD) where there were 4 treatments and 4 replications. The treatments in this study were control/P0 (not vaccinated and given extract), P1 (mouse vaccinated and given 0.5 ml of basil leaf extract), P2 (mouse vaccinated and given 0.7 ml of basil leaf extract), P3 (mouse vaccinated and given aquadest). The results showed that the body temperature of the mice that had increased due to the DPT vaccine had decreased after being given basil leaf extract. The P2 treatment, namely the extract treatment as much as 0.7 ml gave a significant effect on reducing the body temperature of mice
Yenni Aulia Putri, Elita Agustina,
Journal of Pharmaceutical and Health Research, Volume 3, pp 6-9; https://doi.org/10.47065/jharma.v3i1.1317

Abstract:
Pineapple is one of the fruits consumed by the community. Pineapple produces waste in the form of pineapple weevils which are thrown away for nothing. Pineapple weevil can be used as a medium for soaking soybeans in the process of making tempeh. The purpose of this study was to determine the effect of pineapple weevils to increase tempeh protein content, to determine the duration of soaking soybeans in pineapple cone juice which was effective in increasing tempeh protein content, and to determine the feasibility of a reference from the results of research on the effect of soaking soybean seeds in pineapple weevil juice to increase protein content in tempe. The research design used was a completely randomized design (CRD) with 6 treatments and 4 replications, namely P1 (5 hours of immersion), P2 (6 hours of immersion), P3 (7 hours of immersion), P4 (8 hours of immersion), P5 (9 hours of immersion). ) in pineapple weevil juice, and P0 (12 hours of immersion in distilled water as a control). Protein content testing was carried out using the Kjeldahl method through a process of digestion, distillation, and titration carried out at the Goods Quality Testing and Certification Center (BPSMB). Analysis of the protein content data obtained used the ANOVA method and carried out the BNJ further test. The results of data analysis showed an increase in protein content in tempeh soaked with pineapple weevil juice at P1 of 17.39% and showed that the most effective soaking time was 5 hours in pineapple weevil juice
Nurlatifah Nurlatifah, Lidyawati Lidyawati, Rosa Mardiana, Dwi Putri Rejeki, Mona Asiah
Journal of Pharmaceutical and Health Research, Volume 3, pp 10-14; https://doi.org/10.47065/jharma.v3i1.1366

Abstract:
Indonesia is a rich country in terms of flora and fauna diversity. Indonesia's wealth with various types of flora is a highlight for science, one of which is the gotu kola herb (Centella asiatica (L) Urb). The chemical compound asiaticoside is part of the triperoids contained in the gotu kola herb which has the potential as antibacterial, antifungal, antioxidant and anti-cellulite on the skin, suitable for topical preparations such as gels. This study aims to formulate a gel preparation from the ethanolic extract of the gotu kola herb (Centella asiatica (L) Urb) which meets the requirements of a good gel. The formulation of the gel preparation was carried out with concentrations of 20%, 25%, and 30%. Extracted by maceration method using 70% ethanol and in a vacuum rotary evaporator to obtain a thick extract. Evaluation of the gel preparation was carried out by organoleptic test, homogeneity test, pH test, dispersibility test, adhesion test and irritation test. The results of the evaluation carried out with the three concentrations met the requirements of the organoleptic test, homogeneity test, pH test, adhesion test and irritation test, but the ethanol extract gel of the gotu kola herb at concentrations of 20%, 25% and 30% did not meet the requirements for the good dispersion test
Journal of Pharmaceutical and Health Research, Volume 3, pp 23-26; https://doi.org/10.47065/jharma.v3i1.1324

Abstract:
Back ground data obtained from the lhoknga publik helth center in 2018 AKI 0f 453 people and IMR of 4 people, in 2019 AKI of 8 people in 2020 AKI of 11 people in IMR of 2 people a total of 480 pospartum care is on effort mode by midwives, pospartum mothers and famillies with the aim that the nutritional needs of postpartum mothers are fulfillid, personal hygiene is maintained. Research objectives to dermine the relationship between knaowledge and the influence of cultur with hot steam therapy (peusale) on postpartum mothers in lhoknga district, aceh besar regency 2021. This research method used the method the analytikal cross sectional approach wich was carried out on september 14-19-2021 was carried out in the lhoknga sub-district. The population in this study was all 31 postpartum mothers. Sampling using total sampling data analysis using univariatee and bivariate analysis with the chi-squer test method showed a p-value of 0.000 0.05 research results. The results of statistical resets wit chi-squer test showed a p-value of 0.000<0.05, meaning that there was an influence of knowledge with peusale steam therapy culture. Besed on the chi-squer thes table shows a p-value of 0.001<0.05, there is an influence between culture and steam therapy for postpartum mothers in lhoknga district, aceh besar district
Cut Yuliana, , Rini Shafriyani
Journal of Pharmaceutical and Health Research, Volume 3, pp 1-5; https://doi.org/10.47065/jharma.v3i1.1322

Abstract:
Standardization is the process of determining properties based on certain parameters to achieve the same degree of quality. The extract was standardized with two parameters, namely specific and non-specific parameters. So that the efficacy and quality of this soka flower extract can be guaranteed, it is necessary to meet a quality standard for the product/extract material by standardizing the extract. Standardization is carried out so that uniform raw materials can be obtained which can finally guarantee the pharmacological effects of these plants. Standardization is the process of guaranteeing the final product (simplicia, extract or herbal product) to have certain parameter values ​​that are constant and predetermined. The research method is by testing various parameters on the extract, starting with determining the species of soka flower, then calculating the yield, organoleptic testing, water content, water soluble compounds, ethanol soluble compounds. The average water content test result is 9.54% and is still within the permissible standard, the water content in medicinal preparations including extracts should not exceed the 10% limit. Based on the results of determination of water soluble extract content of 20.7% and ethanol soluble extract content of 35.5%. The ethanol soluble extract content was higher than the water soluble compounds, thus the semi-polar compounds in the extract were higher than the polar compounds
Journal of Pharmaceutical and Health Research, Volume 3, pp 19-22; https://doi.org/10.47065/jharma.v3i1.1323

Abstract:
The use of masks is one of the health protocols that must be followed by everyone with discipline. The results of monitoring Compliance with Health Protocols for wearing masks on female students at the Saleha Midwifery Academy Banda Aceh in 2021 are around 75% of all grades 1,2 and 3 students. Research Objectives: to determine the effect of knowledge, environment and behavior on female students at AkbidSaleha Banda Aceh. Research Methods: This study used an analytical method with a Cross Sectional approach which was carried out on 26-27 August 2021. The population in this study were all AkbidSaleha students who totaled 92 people. Sampling using total sampling.Analysis of data using univariate and bivariate analysis with the chi-square method. Results: The results of statistical tests with Chi-Square obtained p Value = 0.000 <0.05, there is an effect of knowledge of student AkbidSaleha with a lack of awareness of the use of masks. While the results of statistical tests with Chi-Square obtained p Value = 0.000 <0.05, there is an environmental influence with a lack of awareness of the use of masks in AkbidSaleha students. And the results of statistical tests with Chi Square obtained p value = 0.000 <0.05, there is an influence of behavior with a lack of awareness of the use of masks in AkbidSaleha students
Lidyawati Lidyawati, Nurul Hidayati, Ria Ceriana
Journal of Pharmaceutical and Health Research, Volume 2, pp 76-81; https://doi.org/10.47065/jharma.v2i3.1267

Abstract:
Katuk (Sauropus androgynus (L.) Merr.) is a plant that has secondary metabolic compounds with various potentials and contains several chemical compounds, including papaverine alkaloids, proteins, fats, vitamins, minerals, saponins, flavonoids and tannins. Katuk leaves can work as antioxidants because they contain phenolic compounds, namely flavonoids. The potential of katuk leaves is also supported by research on pharmacological activities as antibacterial, antihypertensive, antihyperlipidemic, anti-infective, anti-inflammatory, antianemic and increasing milk production. The purpose of this study was to determine whether katuk leaves can be formulated in the form of an ointment. Ointment is defined as a semi-solid preparation that is easily applied and used as an external drug. Ointment is also one of the dosage forms with a semisolid consistency that is oily and generally does not contain water and contains the active ingredient dissolved or dispersed in a vehicle. This study used 4 treatments with various concentrations, namely FO: control formulation of ointment base, FI: formulation of katuk leaf extract ointment preparation with 10% concentration, FII: formulation of katuk leaf extract ointment preparation with 15% concentration, FIII: formulation of katuk leaf extract ointment preparation with a concentration of 20%. Evaluation of the ointment using organoleptic tests, homogeneity, pH, spreadability, stability and irritation. The results of the evaluation carried out on the ointment preparation were stable and did not irritate the skin.
, Fadli Syahputra, Lidyawati Lidyawati
Journal of Pharmaceutical and Health Research, Volume 2, pp 60-66; https://doi.org/10.47065/jharma.v2i3.983

Abstract:
Banda Aceh City is the capital of Aceh Province with the highest number of lung tuberculosis cases. This can be seen from the increase in the incidence of pulmonary tuberculosis in Banda Aceh City. The purpose of this study was to determine the relationship between the role of PMO and family support with pulmonary anti tuberculosis (OAT) drugsThis type of research is analytic descriptive with Cross Sectional Design and the object of research is 128 people with pulmonary TB in Banda Aceh City. The study was conducted for 3 months from August-November 2018 located in all Puskesmas working areas of the Banda Aceh City Health Office data analysis using logistic regression tests. Results PMO supervision, 57.8% received instrumental support, 53.1% received information support, 56.2% received valuation support, 64.0% received emotional support, 63.2% received spiritual support, 50.7% received financial support. statistical results obtained there is a PMO relationship (OR = 18.5 P-Value = 0,000) there is information support (OR = 5.4, P-value = 0.002), there is emotional support (OR = 3.54, P-Value = 0.027), there is support financial (OR = 0 .22, P-Value = 0.018), no instrumental support (OR = 2.5, P-Value = 0.050), no valuation support (OR = 1.22, P-Value = 0.664), no support spiritual (OR = 0.55, P-Value = 0.247)
, Lidyawati Lidyawati, Mutiara Sampoerna
Journal of Pharmaceutical and Health Research, Volume 2, pp 67-69; https://doi.org/10.47065/jharma.v2i3.982

Abstract:
Henna leaves are often used as traditional medicine, including as an antibacterial. Henna leaves contain several active components including phenols and flavonoids which act as antibacterial. The purpose of this study was to determine antibacterial activity of ethanol extract of henna leaves (Lowsonia inermis L.) against Staphyloccocus aureus. This research was conducted using descriptive method. In this study, ethanol extract of henna leaf was made by maceration method. Ethanol extract of henna leaves was tested against Staphylococcus aureus on Nutrient Agar (NA) medium using well diffusion method with 3 extract concentrations, namely 40%, 50% and 90%, tetracycline as positive control and aquadest as negative control with 3 repetitions each. The results of this study showed that inhibition zone diameter of henna leaves extract at a concentration of 40% was 21.29 mm, at a concentration of 50% was 23.1 mm and at a concentration of 90% was 24.4 mm, positive control was 27.93 mm and negative control did not show inhibition zone. The inhibition zone for all concentrations belongs to strong inhibition category.
Novia Agustia,
Journal of Pharmaceutical and Health Research, Volume 2, pp 82-86; https://doi.org/10.47065/jharma.v2i3.1302

Abstract:
Indonesia is a country rich in natural plants that can be used as dyes for cosmetics, one of which is purple sweet potato (Ipomoea batatas L.). This purple sweet potato (Ipomoea batatas L.) grows in the tropics and produces 1.9 million tons of productivity per year. Purple sweet potato (Ipomoea batatas L.) is a natural dye and is safer than synthetic dyes. According to (Dian, 2017), purple sweet potato (Ipomoea batatas L.) contains anthocyanin dyes which play a role in inhibiting the activity of the amulase enzyme and can function as antioxidants. Antioxidants have a function to moisturize the lips and remove dead skin cells, besides that antioxidants are also needed by the body to neutralize free radicals. Lip gloss is a type of lip color preparation that contains high oil so that it gives a moisturizing, shiny or gloss impression. This study used purple sweet potato (Ipomoea batatas L) extract as a natural dye. This study aims to formulate purple sweet potato extract in the form of lip gloss and to see how good the stability of lip gloss is. Purple sweet potato (Ipomoea batatas L) extract was prepared by maceration using 96% ethanol solvent to obtain a liquid extract and then concentrated using a vacuum rotary evaporator to obtain a thick extract. The lip gloss formulation consisted of cera alba, liquid paraffin, vaseline album, emulsifying wax, BHT (Butyl Hydroxy Toluene) nipagin, glycerin, oleum ricini and the addition of purple sweet potato extract coloring. Concentrations used in lip gloss are 0% (F0), 20% (F1), and 35% (F2). Evaluation of lip gloss preparations included organoleptic test, homogeneity, smearing power, pH test, preference and irritation test. The results of the evaluation of the preparations showed that the preparations were homogeneous, and met the requirements well. The results of the smear test showed that the concentrations of 0% (F0), 20% (F1), and 35% (F2) were attached. The results of the preference test showed that at a concentration of 35% (F2) the panelists preferred the most. So it can be concluded that the best preparation is found at a concentration of 35% (F2).
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