Science Review

Journal Information
ISSN / EISSN : 2544-9346 / 2544-9443
Current Publisher: RS Global Sp. z O.O. (10.31435)
Total articles ≅ 176
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Emil Galev, Fedir Markov
Published: 24 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7321

Abstract:
В этой статье обсуждаются некоторые визуальные характеристики ландшафта и приводится несколько конкретных примеров изменений, происходящих во внешнем виде лесных ландшафтов, расположенных вдоль троп наших популярных горных курортов или экологических троп болгарских природных явлений. Это позволяет получить реальное представление о динамике ландшафта по аллеям или тропинкам в лесах и лугах по туристическим маршрутам в Болгарии. Это исследование может помочь прояснить многие вопросы, касающиеся проектирования экологических троп, критериев и стандартов их строительства и их обязанностей по содержанию. Сами болгарские туристы и любители природы создали одни из самых замечательных из них, окруженные красивыми пейзажами гор, водопадов, лесов, скал и ущелий. Ландшафтные архитекторы здесь являются должниками общества, в этом отношении остаются статичными наблюдателями за проблемами туризма. Болгарские экологические тропы предназначены для облегчения доступа туристов к бесчисленным достопримечательностям. Эти туристические маршруты подходят для летних и зимних походов и прогулок и являются отличной идеей для праздничных выходных.
Emil Galev, Fedechko Y.M., Palʹtov Ye. V.
Published: 23 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7320

Abstract:
The aim of the study was to determine the changes in the qualitative and quantitative composition of the microbiota in the neck part of the teeth in the gingival margin of the oral cavity of rats under experimental opioid exposure, its cancellation and comprehensive drug correction using an antibacterial drug. The use of the antibiotic ceftriaxone under conditions of two- and six-week administration of the opioid analgesic nalbuphine, caused the elimination or reduction of the quantitative composition of opportunistic and pathogenic bacterial species, in contrast to the identified changes in the microbiocenosis in the studied microbiotope. antibiotic therapy in the experiment.
Oleksii Minaiev
Published: 19 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7319

Abstract:
Метою дослідження було розробити спосіб визначення топографо-анатомічного взаємозв’язку слізного мішка з оточуючими структурами та оцінити його ефективність при плануванні та виконанні ендоназальної ендоскопічної дакріоцисториностомії (ЕЕДЦРС). Досліджувану групу (1-а група) склали 45 пацієнтів з хронічним дакріоциститом (ХД), яким ЕЕДЦРС була здійснена за розробленою методикою, до групи порівняння (2-а група) було включено 36 хворих, яким після виконання ЕЕДЦРС за розробленою методикою в зону дакріориностоми встановлювали полівінілхлоридний провідник. До контрольної (3-ї) групи увійшли 28 пацієнтів, яким ЕЕДЦРС виконувалась за загальноприйнятою методикою. Для оцінки інформативності методик проведення комп’ютерної томографії (КТ) СВШ і можливості ефективного застосування отриманих КТ-даних, пацієнти 1-ї та 2-ї груп були розподілені на 2 підгрупи: до 1А і 2А були включені пацієнти, яким КТ СВШ проводили за розробленою методикою, а хворим підгруп 1В і 2В – за традиційним алгоритмом. Гіперпневматизація клітин agger nasi виявлена у 14,7% обстежених, запальна патологія в навколоносових пазухах – у 38,5% (p>0,05). Слізна ямка розташовувалась на рівні переднього кінця середньої носової раковини (СНР) в 39,4 % випадках, допереду від нього – у 32,1%, а дозаду – в 14,7 %. У 13,8 % спостереженнях визначити відношення слізної ямки до СНР було утрудненим, ці випадки були в підгрупах 1В, 2В та в 3-й групі (p
Kaminskiy Viacheslav Volodymyrovych, Suslikova Lidiya Viktorivna, Serbeniuk Anastasia Valeriivna, Dercach Andriy Dmytrovych
Published: 6 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7318

Abstract:
The article presents data on the prevalence of thyroid hormonal disorders and the establishment of their relationship between the state of mental health and the functional state of body systems in women who participated in hostilities who suffered contusions. We aimed to assessing the prevalence and effectiveness of the diagnosis of thyroid dysfunction in women of childbearing age with impaired reproductive health who participated in hostilities and suffered contusions, to improve treatment and rehabilitation measures and quality of life of these women.
Kovalyshyn O. A.
Published: 5 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7317

Abstract:
The study of hemodynamic features of the pelvic organs in women is of great clinical importance, since it allows assessing the degree of recovery of endometrial regeneration after menstruation, the possibility of implantating a fertilized egg and placental development. Women who have had menstrual dysfunction in puberty, the determination of qualitative and quantitative parameters of uterine hemodynamics can be useful while choosing treatment tactics, evaluating its effectiveness, and will also provide significant assistance in predicting the prospects for their reproductive health. The purpose of the study. To examine the hemodynamics of uterus and assess the ability of endometrium to implant in women with menstrual dysfunction in puberty with the help of ultrasound and dopplerometry.Materials and methods. To achieve the set goals, 120 women of reproductive age from 19 to 32 years old were examined. By the nature of the disorders, the main group of women (n = 90) with menstrual dysfunction in puberty were divided into 3 subgroups (n = 30): the first group - women with primary oligomenorrhea, the second one - with late menarche, the third one - with pubertal bleeding. The control group consisted of women (n = 30) with the correct rhythm of menstruation in puberty. Results. On the basis of a comparative analysis of the echographic parameters of the size of the uterus in women with menstrual dysfunctions in puberty (main group) and women with the correct rhythm of menstruation (control group), it was found that, on the average stage of endometrial secretion, the volume of the uterus is 1, 2 times smaller in women of the main group (p˂0.05) due to the width of the body of the uterus (p˂0.001). The ratio between the length of the body and cervix in the examined groups did not differ significantly. The thickness of the anterior wall of the uterus is less than the control values in women with late menarche (p˂0.05) and pubertal bleeding (p˂0.01), which was a predictor of the absence of combined uterine pathology. Echographic examination of the thickness of the endometrium at a late stage of the proliferation phase in the examined women did not reveal significant differences with the control group. In the middle stage of the secretion phase, the thickness of the endometrium was less in women, who had menstrual dysfunction in puberty - 9.50 ± 0.27 mm versus 11.38 ± 0.48 mm in the group with the correct menstruation rhythm (p
Osmanova Olha
Published: 1 December 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7298

Abstract:
Проведено наукові дослідження технологічних та екологічних аспектів отримання поверхнево-активних речовин – складних ефірів жирних кислот й цукрів. Традиційно ефіри жирних кислот й цукрів синтезують хімічними методами в екстремальних умовах (з застосуванням високої температури й тиску, у присутності лужних або кислотних каталізаторів). Заміна хімічних процесів на ферментні є прикладом «зеленого» виробництва. Наведено різні підходи застосування неводних середовищ для проведення біокаталітичної етерифікації. Визначено найбільш екологічний підхід – етерифікація у середовищі без розчинника, що забезпечує збереження активності ферментів, відсутність витрат на використання та відновлення розчинника, полегшує подальшу очистку, зменшують вплив на екологію, підвищує особисту безпеку.
Tetiana Kalynychenko, Anoshyna Militina, Balan Valentyna, Parubets Lidiia, Yagovdik Maryna
Published: 30 November 2020
Science Review; doi:10.31435/rsglobal_sr/30122020/7297

Abstract:
An in-depth study of the oxidative homeostasis state into cell suspensions that contain hematopoietic stem cells is one of the key points for understanding ways to improve technologies for long-term storage of this material. Compounds with antioxidant action are considered promising additional cryoprotectants. Intensification of lipid peroxidation processes is one of the main factors causing disturbances in the barrier properties of cell membranes. Comparative analysis of changes in lipid peroxidation parameters during the cryopreservation-deconservation cycle showed that antioxidants-membrane protectors with different mechanisms of action (B-complex vitamins; α-lipoic acid, thiazotic acid morpholinium salt, 2-ethyl-6-methyl-3-hydroxy pyridine succinate) have similar features of a positive effect on the oxidative status of umbilical cord blood nuclear cell suspensions during cryopreservation. However, 2-ethyl-6-methyl-3-hydroxy pyridine succinate has a statistically significant advantage over α-lipoic acid and thiazotic acid morpholinium salt in terms of the conjugate formation dynamics during phospholipid peroxidation, which can be associated with its direct antioxidant effect.
O. Abrahamovych, S. Guta, O. Synenkyi, V. Chemes
Published: 25 October 2020
Science Review; doi:10.31435/rsglobal_sr/31102020/7222

Abstract:
Actuality. The infection with cytomegalovirus (CMV) and Epstein-Barr virus (EBV) in the patients with systemic lupus erythematosus (SLE) is of particular interest to researchers. SLE is a chronic autoimmune disease of unknown etiology that is characterized by multisystemic lesions and is potentially life-threatening [1, 2, 3]. The severity of the problem is caused by the fact that active viral infection can change the manifestations of SLE, but these changes are not always specific, so primary care physicians have no reason to suspect active virus infection at the first stage of examination of SLE patients and prescribe expensive direct virological tests accordingly. It has not been definitively established yet which complaints are the most meaningful regarding the presence of active viral infection in patients with SLE.The purpose of the research was to study complaints in SLE patients with active cytomegalovirus and Epstein-Barr virus infection and determine their diagnostic value. Materials and methods. We randomly enrolled 120 SLE patients – 15 men (12.50%) and 105 women (87.50%) aged 18 to 69 years. All patients received treatment at the Rheumatology Department of Lviv Regional Clinical Hospital in 2014-2019. The diagnosis of SLE was established based on the diagnostic criteria of the American College of Rheumatologists (ACR, 1997). In addition, IgM and IgG antibodies to serum viruses were detected for the diagnosis of CMV and EBV infection. To confirm the presence of active viral infection, viruses were detected in media (CMV - urine, blood; EBV - oral mucosa, blood) by polymerase chain reaction, resulting in 28 patients with SLE (23.33%) detected active CMV infection, in 21 patients with SLE (17.50%) - active EBV infection and in 15 patients with SLE (12.5%) - a combination of active CMV and EBV infection. To achieve the purpose of the study, we identified three steps: the first step was to analyze complaints in patients with SLE with active CMV infection and determine their diagnostic value, the second - in the analysis of complaints in patients with SLE with active EBV infection and clarify their diagnostic values and the third - in the analysis of complaints in patients with SLE with a combination of active CMV and EBV infection and clarification of their diagnostic value. We identified three steps: the first step was to analyze complaints in patients with SLE with active CMV infection and determine their diagnostic value, the second - in the analysis of complaints in patients with SLE with active EBV infection and clarify their diagnostic values and the third - in the analysis of complaints in patients with SLE with a combination of active CMV and EBV infection and clarification of their diagnostic value.Statistical analysis was performed by calculating the chances of establishing the phase of CMV and EBV infection in patients with SLE, using a separate feature - a marker that can be detected during the initial examination of the patient. The probable probability of active infection was determined using indicators of sensitivity, specificity and accuracy [4]. The actual material was processed on a personal computer in MS Excel and SPSS on the basis of conjugation tables with calculation of diagnostic value indicators. The association between active infection and a particular patient complaint was considered to be confirmed when the coefficient of association exceeded 0.5 (or 0.3 for the coefficient of contingency). Research results. It was found that in patients with SLE the presence of active cytomegalovirus infection among the main complaints significantly more often indicate the presence of myalgias (coefficient of association 0.79) or fever (0.51), or chills of the extremities (0.51), or arthralgia (coefficient of contingent 0.31). The presence of active virus Epstein - Barr infections are significantly more often evidenced by the presence of myalgias (coefficient of contingent 0.31) or sleep disorders (coefficient of association 0.84), or mood swings (0.74), or fever (0.61), or the appearance of new rashes (0.53). On the presence of a combination of active cytomegalovirus and virus Epstein - Barr infections significantly more often indicate complaints of sleep disturbances (coefficient of association 0.97) or mood swings (0.83), or a feeling of dryness in the eyes (0.51), or fever (0.50). Conclusions. The presence of active cytomegalovirus infection in patients with systemic lupus erythematosus among the main complaints often indicates the presence of myalgias or fever, or chills of the extremities, or arthralgia, the presence of active virus Epstein - Barr infection - myalgia or sleep disturbances, or mood swings, or fever, or the appearance of new rashes, the presence of their combination - sleep disturbances or mood swings, or a feeling of dryness in the eyes, or fever, which can be used in the diagnostic algorithm. The established patterns of complaints allow us to reasonably suspect in patients with systemic lupus erythematosus the presence of active cytomegalovirus and Epstein-Barr virus infection, the final verification of which requires the use of direct serological tests.
Денисова М. Ф., Букулова Н. Ю.
Published: 16 October 2020
Science Review; doi:10.31435/rsglobal_sr/31102020/7221

Abstract:
This article presents frequency of occurrence of clinical forms of the disease depending on the localization and activity of the inflammatory process, their age and gender differences, risk factors and disease triggers, based on a retrospective analysis of 116 cases of children with ulcerative colitis at the age of 4-18 years. Comparative clinical, laboratory and endoscopic characteristics of total, segmental and distal colitis have been also analyzed. It was found that clinical activity of total colitis is characterized by more severe course of the disease, accompanied with systemic and local extraintestinal manifestations (OR = 4,504±0,506, p
Iryna Novakovska, Igor Slavin, Nataliia Ishchenko, Liliia Skrypnyk
Published: 13 October 2020
Science Review; doi:10.31435/rsglobal_sr/31102020/7219

Abstract:
The article analyses peculiarities and specific features of the use of alternative power and fuel capacities during its formation in the sphere of air transport land management. The following elements of the system for producing power-efficient resources comprises have been considered. It substantiates the necessity to involve the concepts of design and use of a modern power-efficient airport infrastructure and its connection with sound and efficient land management. The authors consider the experience of other countries and the perspectives of alternative power and fuel resources – the "green areas". Also It have been established that every new project of an airport or a reconstructed one, shall be focused on meeting the latest standards of minimization of the airport’s impact on the environment and on the reduction of climatic changes, connected with its infrastructure and activities. Within the studies of the experts in the sphere of the aviation industry, and the members of ICAO council, it have been considered the concept of development and use of a modern, power-efficient airport infrastructure. The authors have proposed a modification of the methodological calculation of resource conservation indicators by reducing fossil fuel emissions within the airport and surrounding areas.
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