Open Journal of Depression

Journal Information
ISSN / EISSN : 21699658 / 21699674
Current Publisher: Scientific Research Publishing, Inc. (10.4236)
Total articles ≅ 72
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Latest articles in this journal

A. Bloore Rebecca, E. Jose Paul, Joshanloo Mohsen, Rebecca A. Bloore, Paul E. Jose, Mohsen Joshanloo
Open Journal of Depression, Volume 9, pp 1-16; doi:10.4236/ojd.2020.91001

Abstract:The literature is beginning to document how and for whom “fear of happiness” (happiness aversion, i.e. the expectation that being happy can have negative consequences) is predictive of psychological outcomes. We sought to determine whether hope, an important protective factor against depressive symptoms, might mediate and moderate the relationship between happiness aversion and depression. In a dataset of 588 undergraduate psychology students, evidence was found that hope functioned as a mediator as well as a buffer in the relationship between happiness aversion and depression. In addition, exploratory analysis of a small longitudinal dataset (N = 74) suggested that hope also played the same roles in the relationship between fear of happiness and depression over time. These findings suggest that interventions that create hope can be effective in disrupting the relationship between happiness aversion and depressive symptoms.
Chris Griffiths, Alex O’Neill-Kerr, Robert De-Vai, Tina Sore, Ksenija Da Silva
Open Journal of Depression, Volume 8, pp 59-70; doi:10.4236/ojd.2019.83007

Abstract:Objective: The aim of this paper is to present the clinical data analysis results from a service delivering ketamine infusion, repetitive transcranial magnetic stimulation (rTMS) and electroconvulsive therapy for people with treatment resistant depression (TRD). Methods: The study was a retrospective investigation of routinely collected data on patients receiving ketamine infusion between 2017 and 2019. Measures used were the clinician-rated Clinical Global Impression (CGI) and self-reported Beck Depression Inventory (BDI) and Quick Inventory of Depressive Symptomatology (QIDS-SR). The outcome data of 28 patients with TRD were analysed. A minimum course of treatment was defined as three ketamine infusions. Results: Response combined with partial response, response, and remission rates respectively were 42.3%, 23.1% and 4.2% for the BDI; 18.2%, 9.1% and 0% for the QIDS-SR; 50%, 18.2% and 4.6% for the CGI. There was a statistically significant improvement on the BDI with a medium effect size (0.63). There was not a significant improvement in the CGI or QIDS-SR. Conclusions: The results show a mixed picture the impact ketamine on symptoms of depression in TRD over the course of multiple infusions. The results need to be viewed in the context of clinical outcome data collection: outcome scores are taken prior to treatment and so are at a point when ketamine is not having an active effect. The findings can inform the availability of ketamine infusion as a treatment option for TRD where treatment adhering to national guidelines has not succeeded. A qualitative investigation of the experience of people receiving ketamine would provide further insights.
Sefa Bulut
Open Journal of Depression, Volume 8, pp 41-47; doi:10.4236/ojd.2019.82005

Weiren Wang, Yanqiong Ouyang
Open Journal of Depression, Volume 8, pp 48-57; doi:10.4236/ojd.2019.82006

Alfred Anselme Dabilgou, Desiré Nanema, Alassane Dravé, S. P. Sawadogo, Julie Marie Adeline Kyelem, Christian Napon, Jean Kaboré
Open Journal of Depression, Volume 8, pp 29-40; doi:10.4236/ojd.2019.81004

Felipe Vázquez-Estupiñan, Rocío Herrera-Márquez, José Antonio Mondragón-Herrera, Guillermina Lara-Pérez, Gabriel Manjarrez-Gutiérrez
Open Journal of Depression, Volume 8, pp 5-15; doi:10.4236/ojd.2019.81002

Chris Griffiths, Ksenija Maravic Da Silva, Rob De Vai, Alex O’Neill-Kerr
Open Journal of Depression, Volume 8, pp 16-28; doi:10.4236/ojd.2019.81003

Ayina Lionel Wamia, Ngachangong Victorine
Open Journal of Depression, Volume 8, pp 71-84; doi:10.4236/ojd.2019.84008

Abstract:Depression is the most common neuropsychiatric mental condition found among people living with HIV (PLHIV). Despite its high prevalence, depression remains under diagnosed amongst PLHIV, and determining its prevalence is very cumbersome. As a mental condition, it has been associated with increased comorbidity, non-adherence to HAART, suicidal attempts, unsafe sex practice, just to name a few. Support groups have been shown to play an important role in the improvement of the quality of life of PLHIV and could be a means of managing depressive symptoms that arise in their lifetime. The aim of this research was to assess the role of support groups in the management of depression amongst PLHIV at the Bamenda Regional Hospital (BRH). This was a hospital based, observational cross sectional and descriptive study used to gather information from, one hundred and fifty two (152) HIV positive patients sticking to appointments at the treatment centre of BRH. The patient health questionnaire 9 (PHQ-9) was the screening tool for depression. Minimal, mild, moderate, moderately severe and severe depression constituted the levels of depression in which participants with depressive symptoms felt. A score of nine and above (≥9) was considered positive for depression. Further, the role of support groups were assessed through other questions that constituted the questionnaire and the activities carried out in support groups were observed and compared to standards of practice. Analysis revealed that 29.61% (95% CI: 22.5% - 35.7%) were positive for depression, and 108 (71.06%) participants presented with depressive symptoms. The role of support groups to participants was that it helps them in adhering to medication, filling hopeful and aiding them in disclosing their seropositive status to family members. The student t-test: t (70, N = 71) = −0.468, p = 0.641, showed no significant difference amongst support groups attendees and non-attendees, however, they are important to PLHIV and its practice at the level of Bambui District Hospital should be improved.
Obianma Nneka Onya, Chinenye Otorkpa
Open Journal of Depression, Volume 7, pp 51-59; doi:10.4236/ojd.2018.73004

Abstract:Introduction: Globally, the burden of depression is on the increase especially among women. The increased prevalence of depression correlates with hormonal changes in women, suggesting that female hormonal fluctuations may be a trigger for depression. Hence this study sought to determine the prevalence and socio-demographic pattern of depression among pre- and post-menopausal women. Methodology: A cross-sectional design comprising of pre- and post-menopausal women attending the General Outpatient Department of the Federal Medical Centre in Lokoja, North-Central region of Nigeria was employed in this study. Data on depression were collection using the Center for Epidemiologic Study Depression (CES-D) questionnaire, a validated and reliable tool for assessment of depression. Descriptive and inferential statistics were performed using Centers for Disease Control and Prevention (CDC) Epi Info version 7. Statistical significance was set at level of 0.05. Results: A total of 277 pre-menopausal and 103 post-menopausal women were involved in the study. The prevalence of depression was higher among post-menopausal women (45.6%) in comparison to pre-menopausal women (35.4%). There was no significant relationship between demographic characteristics and depression in both groups of the study (p > 0.05). Conclusion: This study noted that unlike the pre-menopausal population, almost half of the post-menopausal women had depression. Hence, routine screening for depression among post-menopausal women is advocated for timely intervention irrespective of their socio-demographic status.