ACS Catalysis

Journal Information
ISSN / EISSN : 2155-5435 / 2155-5435
Current Publisher: American Chemical Society (ACS) (10.1021)
Former Publisher:
Total articles ≅ 8,869
Current Coverage
SCOPUS
SCIE
COMPENDEX
Archived in
SHERPA/ROMEO
Filter:

Latest articles in this journal

Spencer P. Heins, Patrick E. Schneider, Amy L. Speelman, ,
ACS Catalysis pp 6384-6389; doi:10.1021/acscatal.1c00781

The publisher has not yet granted permission to display this abstract.
Hao Yan, Qi Shen, Yinghao Sun, Siming Zhao, Ruilong Lu, Mengcong Gong, , Xin Zhou, , , et al.
ACS Catalysis pp 6371-6383; doi:10.1021/acscatal.1c01566

The publisher has not yet granted permission to display this abstract.
Caitlin V. Kozack, Stephen J. Tereniak, Jonathan N. Jaworski, Bao Li, David L. Bruns, Spring M. M. Knapp, ,
ACS Catalysis pp 6363-6370; doi:10.1021/acscatal.1c01074

The publisher has not yet granted permission to display this abstract.
Tao Li, Karl N. McCabe, , Xuebing Leng,
ACS Catalysis pp 6348-6356; doi:10.1021/acscatal.1c00463

The publisher has not yet granted permission to display this abstract.
Mingxiang Zhu,
ACS Catalysis pp 6334-6342; doi:10.1021/acscatal.1c01600

The publisher has not yet granted permission to display this abstract.
Sandro Fischer, , Alexandria D. Liang
ACS Catalysis pp 6343-6347; doi:10.1021/acscatal.1c01470

Abstract:
Artificial metalloenzymes (ArMs) are created by embedding a synthetic metal catalyst into a protein scaffold. ArMs have the potential to merge the catalytic advantages of natural enzymes with the reaction scope of synthetic catalysts. The choice of the protein scaffold is of utmost importance to tune the activity of the ArM. Herein, we show the repurposing of HaloTag, a self-labeling protein widely used in chemical biology, to create an ArM scaffold for metathesis. This monomeric protein scaffold allows for covalent attachment of metathesis cofactors, and the resulting ArMs are capable of catalyzing ring-closing metathesis. Both chemical and genetic engineering were explored to determine the evolvability of the resulting ArM. Additionally, exploration of the substrate scope revealed a reaction with promising turnover numbers (>48) and conversion rates (>96%).
Yong Guan, Tadas A. Buivydas, Remy F. Lalisse, Jonathan W. Attard, Rameez Ali, Charlotte Stern, Christopher M. Hadad,
ACS Catalysis pp 6325-6333; doi:10.1021/acscatal.1c01095

The publisher has not yet granted permission to display this abstract.
Fangfang Guo, Jiean Chen,
ACS Catalysis pp 6316-6324; doi:10.1021/acscatal.1c01908

The publisher has not yet granted permission to display this abstract.
Yiyang Lin, Kang Liu, Kejun Chen, Yan Xu, Hongmei Li, , Ying-Rui Lu, Ting-Shan Chan, , Junwei Fu, et al.
ACS Catalysis pp 6304-6315; doi:10.1021/acscatal.0c04966

The publisher has not yet granted permission to display this abstract.
Back to Top Top