Biomedical Journal of Scientific & Technical Research (BJSTR) is a multidisciplinary, scholarly Open Access publisher focused on Genetic, Biomedical and Remedial missions in relation with Technical Knowledge as well. Our BJSTR maintains a scrupulous, methodical, fair peer review System. Besides, quality control is riveted in each step of the publication process.

Author Affiliations 1Department of Physical Therapy Chunnam Techno University, Republic of Korea 2Department of Physical Therapy Sunhan Hospital, Republic of Korea 3Department of Physical Therapy Nambu University, Republic of Korea Received: August 30, 2020 | Published: September 09, 2020 Corresponding author: Dong-Kyu Lee, Department of Physical Therapy Sunhan Hospital, Republic of Korea DOI: 10.26717/BJSTR.2020.30.004923 The purpose of this study is to examine the effects of circle-ring resistance exercise according to vibration frequency on the trunk muscle thickness of previous low back pain patients. 39 patients who previously had low back pain were selected and were randomly assigned one of the three groups: 8Hz vibration circle-ring resistance exercise group, 30Hz vibration circle-ring resistance group, and stabilization exercise group to have 13 subjects in each. The circle-ring resistance exercise according to vibration frequency was conducted in a vibration exercise apparatus 3 times a week for 30 minutes for a total of 8 weeks. The study used an ultrasonic instrument to measure trunk muscle thickness before as well as 4 and 8 weeks after the experiment. The results indicated that the external oblique and the internal oblique had significant differences in time-to-time and time-group interaction (p0.05). Transversus abdominis showed significant differences in time-to-time and time-and-group interaction as well as inter-group interaction (p Keywords: Vibration; Circle-Ring Exercises; Trunk Muscle Thickness

Author Affiliations 1Instituto Global de Excelencia Clínica Keralty, Centro de Evaluación de Tecnologías en salud, Departamento de gestión de dispositivos médicos, Bogotá-Colombia. 2Instituto Global de Excelencia Clínica Keralty, Centro de Evaluación de Tecnologías en salud, Departamento de estudios económicos, Bogotá-Colombia. 3Agencia de Calidad y seguridad Keralty, Bogotá- Colombia. 4Instituto Global de Excelencia Clínica Keralty, Centro Iberoamericano de investigación en Salutogénesis y bienestar, Bogotá-Colombia. 5Instituto Global de Excelencia Clínica Keralty, Centro de Medicina basada e informada en la evidencia, Bogotá-Colombia. 6Instituto Global de Excelencia Clínica Keralty, Centro de Evaluación de Tecnologías en salud, Bogotá-Colombia. 7Instituto Global de Excelencia Clínica Keralty, Bogotá-Colombia. 8Grupo de Investigación Translacional-Fundación Universitaria Sanitas 9Keralty 10Purchasing department Keralty, Bogotá-Colombia Received: August 19, 2020 | Published: September 09, 2020 Corresponding author: Claudia Guevara Pérez, Instituto Global de Excelencia Clínica Keralty, Centro de Evaluación de Tecnologías en salud, Departamento de gestión de dispositivos médicos, Av. Calle 127 # 20 – 56 6th floor, Colombia DOI: 10.26717/BJSTR.2020.30.004910 Introduction: The pandemic caused by the novel coronavirus SARS-CoV-2 has increased the demand for health services and thereby created a shortage of personal protective equipment for health workers. In a real scenario of a shortage of N95 filtering facepiece respirators, organizations such as the Centers for Disease Control and Prevention recommend the alternative use of reusable elastomeric respirators. Objective: To perform a hospital-based health technology assessment of reusable half-face and full-face elastomeric respirators for use in intensive care units focused on patients with a confirmed or suspected diagnosis of COVID-19. Method: The process was carried out with a multicriterion decision approach to assess six domains according to the recommendations of the European Network for Health Technology Assessment. Results: The available evidence on reusable elastomeric respirators in healthcare settings is scarce. The studies found allow us to recommend the use of elastomeric respirators in a conditional context of a shortage of N95 respirators in specific areas, and our analysis shows that they are less expensive. These respirators are the first-line alternative to scarce N95 respirators and have cost advantages in the simulation scenario. A training, monitoring, and assessment strategy must be in place for the implementation of reusable elastomeric respirators. At the organizational level, the use of these respirators is perceived as safe and comfortable. Conclusions: This hospital-based health technology assessment shows that reusable elastomeric respirators can be used in intensive care units as a rational alternative to disposable N95 respirators whose shortage is caused by a pandemic. Keywords:Technology Assessment; Hospital-Based; Pandemics; Personal Protective Equipment; Respiratory Protective Devices; Mask Abbreviations: PPE:Personal Protection Equipment; CDC: Centers for Disease Control; WHO: World Health Organization; RERs: Reusable Elastomeric Respirators; HTA: Health Technology Assessment; ICU: Intensive Care Unit; OSHA: Occupational Safety and Health Administration; NIOSH: National Institute for Occupational Safety and Health

Author Affiliations Department of Physical Therapy, Takarazuka University of Medical and Health Care, Japan Received: August 24, 2020 | Published: September 01, 2020 Corresponding author: Department of Physical Therapy, Takarazuka University of Medical and Health Care, Hanayashiki- Midorigaoka 1, Takarazuka-city, Hyogo, 666-0162 Japan DOI: 10.26717/BJSTR.2020.29.004877 Excellent osteoconductivity or osseointegration of biomaterial is very important for the stability of artificial joints and dental implants in clinical field.Against this background, We have already reported that the low-intensive pulsed ultrasound wave stimulation (LIPUS) could accelerate the bone-like hydroxyapatite precipitation on the bioactive material surface, which corresponds to osseointgration. The purpose of this study was to investigate the difference between the kinds of biomaterials the osseointegration enhanced by LIPUS in vitro. Hydroxyapatite (99.9%) and Bio-active titanium were soaked in simulated body fluid under the LIPUS radiation, and accessed by scanning electron microscope and X-ray diffraction, the mass of precipitation was measured.In a result, bio-active titanium showed the more rich bone-like apatite formation on the surface than hydroxyapatite. These facts suggested that the formation of bone-like apatite might depend on the initial epitaxial nucleation growth on the biomaterial surface. Keywords: Low-Intensive Pulsed Ultrasound Wave Stimulation (LIPUS); Hydroxyapatite; Bio-Active Titanium; Osseointegration; Simulated Body Fluid (SBF)

Author Affiliations 1Maria Cecilia Hospital, GVM Care & Research Cardiac Surgery Unit, Italy 2Late Professor and Chairman, Department of Medicine and Division of Clinical Pharmacology, School of Medicine of the University of Modena and Reggio Emilia, Italy Received: August 22, 2020 | Published: August 31, 2020 Corresponding author: Giorgio Noera, Maria Cecilia Hospital, GVM Care & Research Cardiac Surgery Unit, Italy DOI: 10.26717/BJSTR.2020.29.004870 The pathophysiology of multiple organ failure is reviewed in the light of the most recent experimental and clinical data. The current therapeutic approaches are alike discussed. The basically unchanged mortality rate of this condition reflects the basically unchanged therapy guidelines. Of the three really innovative treatments that have been proposed during the last forty years (naloxone; vagus stimulation; melanocortins), the first two have been abandoned after an initial, rather entusiasthic endorsement, and the third has been neglected: the reasons are discussed. Keywords: Shock; MOF;MODS;SIRS;Shock Treatment; NaloxoneMelanocortins; Vagus Stimulation Abbreviations: MODS: Multiple Organ Dysfunction Syndrome; MOF: Multi Organ Failure; SIRS: Systemic Inflammatory Response Syndrome; MAPKs: Mitogen-Activated Protein- Kinases; NO: Nitric Oxide; MCS: Mechanical Circulatory Support; POMC: Proopiomelanocortin

Total knee arthroplasty (TKA) has been more prevalent due to the increase in life expectancy and is already one of the most common elective procedures performed in the United States...

Author Affiliations University of Rochester, Medical Center, Rochester, USA Received: August 10, 2020 | Published: August 25, 2020 Corresponding author: Dr. Zaid Al Jebaje, Fellow of Cardiovascular Medicine, University of Rochester, Department on Medicine, Division of Cardiology, Rochester, NY, 601 Elmwood Avenue, Rochester, NY 14642, USA DOI: 10.26717/BJSTR.2020.29.004848 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID- 19) has had large implications in patients with preexisting cardiovascular conditions. COVID-19 has a high inflammatory burden which places patients at risk for developing repolarization changes with resultant prolongation of the QT syndrome and Torsades de Pointes (TdP). This is potentially further exacerbated by medications being used to treat COVID-19. However, there have been no cases of TdP reported without a specific link to medication during a COVID-19 infection. Abbreviations: ARDS: Acute Respiratory Distress Syndrome; ICU: Intensive Care Unit; CVD: cardiovascular disease; ACE2: Angiotensin-Converting Enzyme 2; CRS: Cytokine Release Syndrome; LQTS: Long QT Syndrome; SARS: Severe Acute Respiratory Syndrome; HERG: Human Ether- a-go-go-Related Gene

Lumbar disc degenerative disease with canal stenosis is considered a disease resulting from aging because it affects the intervertebral discs through progressive degeneration and, at the same time, arthrosis of the posterior articular facets occurs, resulting in a narrowing of the spine...

Author Affiliations 1Med Byte Ltd, Russia 2Laboratory of Information Technologies and Mathematical Simulation, Russia 3Software Engineering, Russia Received: August 01, 2020 | Published: August 13, 2020 Corresponding author: Valery Muzhikov, Gzhatskaya str. 5/3-139, St. Petersburg, Russia DOI: 10.26717/BJSTR.2020.29.004814 Background: Every living matter is characterized by rhythm in the basis of its existence and the laws of symmetry apply in it. System of acupuncture channels (АС) reflects the basic processes in the body, rhythm and symmetry are also peculiar to them, which through them can be estimated much more simply than, for example, based on biochemical or physiological parameters of the body. Methods: A patient with type 1 diabetes performed 43 Akabane tests at different times of the day for 18 days. With each test, she recorded blood sugar, insulin dose and assessed the effect on the body of various other factors in arbitrary units (from 1 to 10) with an assessment of their effect on the level of glycemia using regression and correlation analysis. The rhythmic activity of АС was also analyzed using Cosinor analysis. Results: It was found that the influence on the level of glycemia through certain AС is exerted by many external and internal factors. In routine monitoring of blood sugar, they cannot be foreseen, because blood glucose itself is the final product in a large chain of metabolic reactions that cannot be controlled in this way. The activity of certain AС reflects these influences and changes cyclically, which can be used to evaluate biorhythms. It was shown that a correctly selected medicine at an individual level restores symmetry in the body, which is broken at different levels from the effects of the disease. Conclusion: Using the regression analysis and the Cosinor method for assessing the contribution of AС to glycemia, it is shown that different AС have different phases, amplitudes and periods of biorhythms, therefore, due to their interference within the same regression model, sharp fluctuations glycemia are possible, which can be predicted in time. By assessing the asymmetry at the AС level in the body, it is also possible to carry out individual selection of drugs and their doses Keywords: Akabane Test; Medicine Action; Chronopharmacology; Kosinor - Analyses; Telemedicine

Seven billion people all over the world are currently threatened by the Coronavirus Disease 2019 (COVID-19) virus, and the scientific community has been mobilized to the best of its ability to counteract this threat...