Jurnal Sains dan Kesehatan

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ISSN / EISSN : 2303-0267 / 2407-6082
Total articles ≅ 293
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Vaya Luthfi Salsabila Anshory, Nurul Hasanah, Novia Fransiska Ngo
Jurnal Sains dan Kesehatan, Volume 4, pp 89-98; https://doi.org/10.25026/jsk.v4i1.844

Abstract:
Nausea and vomiting affect up to >50% of pregnancies. Hyperemesis gravidarum is vomiting that occurs in early pregnancy until 20 weeks of gestation. The incidence of hyperemesis gravidarum in Indonesia is still quite a lot. The cause of this disease cannot be known with certainty, but it is carefully adjusted by thyroid hormone, Helicobacter pylori infection, and psychology. This study use literature review as a research method. This literature review study aims to determine the relationship between psychology on the hyperemesis gravidarum occurrence. Searches were performed by searching articles using electronic databases or search engines i.e Google Scholar, Harzing’s Publish, and Pubmed. The year of publication was limited between 2016 and 2021 in Indonesian and English language. The results were obtained 27 studies from International and Regional journals that are suitable with the inclusion criteria. The number of samples was 654.363 pregnant women are devided into case and control groups. The results of this literature review showed that psychology was found to be associated with hyperemesis gravidarum (96,3%). It can be concluded that psychological factors were found to be associated with the hyperemesis gravidarum occurrence.
Usman Usman, Dwi Fildzania, Imam Fauzi
Jurnal Sains dan Kesehatan, Volume 4, pp 28-35; https://doi.org/10.25026/jsk.v4i1.724

Abstract:
Penelitian ini bertujuan untuk mengetahui kandungan senyawa metabolit sekunder dan antioksidan serta antidiabetes ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata. Tumbuhan sampel yang digunakan diambil di pesisir pantai Muara Badak. Sampel daun mangrove R. mucronata yang telah dikeringkan diekstrak dengan metode maserasi menggunakan pelarut methanol dan dilanjutkan dengan proses ekstraksi secara partisi cair-cair menggunakan pelarut n-heksan, diklorometan dan etil asetat. Ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata dilanjutkan dengan uji fitokimia menggunakan uji warna, uji aktivitas antioksidan dengan metode DPPH, uji antidiabetes menggunakna metode uji toleransi glukosa oral (UTGO). Hasil uji fitokimia ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata positif mengandung senyawa metabolit golongan alkaloid, flavonoid, tannin, dan fenolik. Hasil uji aktivitas antioksidan dari ekstrak total diklorometan memiliki nilai IC50 sebesar 70,38 ppm dan hasil uji antidiabetes berdasarkan persentase penurunan kadar glukosa darah mencit yang paling tertinggi terjadi pada mencit kelompok V dengan dosis 250 mg/kgBB yaitu sebesar 68,78%. Hasil uji aktivitas antioksidan dari ekstrak total etil asetat memiliki nilai IC50 sebesar 59,89 ppm sedangkan untuk hasil uji antidiabetes ekstrak etil asetat berdasarkan persentase penurunan kadar glukosa darah mencit yang paling tertinggi terjadi pada mencit kelompok IV dengan dosis 125 mg/kgBB yaitu sebesar 28,89%. Berdasarkan data tersebut dapat dikatakan bahwa ekstrak total diklorometan dan etil asetat memiliki aktivitas antioksida dengan kategori kuat. Ekstrak diklorometan berpotensi sebagai antidiabetes karena mampu menurunkan kadar glukosa dengan persentase penurunan kadar glukosa yang tertinggi.
Dwi Fitrah Wahyuni, Mardiah Mustary, Syafruddin Syafruddin, Deviyanti Deviyanti
Jurnal Sains dan Kesehatan, Volume 4, pp 48-55; https://doi.org/10.25026/jsk.v4i1.875

Abstract:
Peel off face mask is one type of face mask that has advantages in its use, namely that it can be easily removed or lifted like an elastic membrane. The purpose of this study was to determine the formulation of a peel off gel mask preparation made from Ambon banana peel (Musa paradisiaca var). The gel mask formulation was made on the basis of Polyvinyl Alcohol (PVA) with a concentration of 7%. The active ingredient used is Ambon banana peel which contains vitamin B6, carbohydrates, phosphorus, protein, vitamin C, and several other substances that are useful for body health and beauty as well as other ingredients such as flavonoids, tannins, and saponins. This study used experimental methods to determine the best proportion of masks from Ambon banana peels which included organoleptic tests, homogeneity, drying time, pH and dispersion. The results of the observations were organoleptic test with a characteristic brown odor and semi-solid form, homogeneity test from day 1/14 for all homogeneity formulas, pH test from day 1/14 all formulas had a good pH because they were still in range 4.5-6.5 which is 5, the dry preparation test on the 1st/14th day formula 1, 2 has good drying power because it is still in the drying time requirement of 15-30 minutes while formula 3 has a high drying power. less good than the 1st/14th day because it exceeded the drying time of the preparation, and the dispersion test on day 1 of formulas 1 and 2 met the requirements while formula 3 did not meet the requirements while on day 14 all formulas met the requirements From the results of the research that has been done, it can be concluded that the Ambon banana peel can be formulated into a peel off gel mask preparation.
Dea Pratiwi Sadaningsih, Listiyawati Listiyawati, Imran Irsal
Jurnal Sains dan Kesehatan, Volume 4, pp 71-78; https://doi.org/10.25026/jsk.v4i1.1097

Abstract:
Dental care has been significantly impacted by the COVID-19 pandemic. Aerosol dispersal in most dental procedures can present a high risk of infection to both dentists and patients. Dental Polyclinic of Tk.IV Hospital is one of the hospitals in Samarinda that is still operating during the pandemic COVID-19, implementing health protocols such as limiting dental procedures and reducing dental visits. These restrictions will probably affect patients’ perceptions of service quality they receive and show health quality service provided by the hospital. This study aims to describe the level of satisfaction towards service quality at the Dental Polyclinic of Tk.IV Hospital Samarinda during the COVID-19 pandemic. This descriptive observational study was based on interview and questionnaire administration for 104 patients with inclusion and exclusion criteria. Two variables observed in this study were service quality with SERVQUAL dimension and patients’ level of satisfaction. The findings revealed that the average patients’ level of satisfaction was 92.62%. The dimensions of tangible 91.4%, reliability 92.8%, responsiveness 92.55%, assurance 93.93%, and empathy 92.45% were satisfactory, ranging from 81% and 100%. In general, according to those five dimensions, patients reported that the service quality was excellent and very satisfactory
Ulyati Ulfah, Eli Halimah, Auliya A Suwantika
Jurnal Sains dan Kesehatan, Volume 4, pp 19-27; https://doi.org/10.25026/jsk.v4i1.761

Abstract:
Diabetes mellitus is one of chronic diseases with high treatment cost. Purpose of this research was to analyze the cost-effectiveness of (Prolanis) for patients with type 2 DM and to establish the most significance parameter affecting the cost-effectiveness value. This study is a non-experimental retrospective by collecting medical record data of Prolanis patients with type 2 DM at Bandung Health Center during 2015 and 2016 with 246 samples that met the inclusion criteria. Cost-effectiveness analysis was conducted by calculating Average Cost Effectiveness Ratio (ACER) and Incremental Cost Effectiveness Ratio (ICER). In particular, sensitivity analysis was conducted to investigate the most significance parameter affecting those ratios. The result of unpaired t test confirmed that there was not significance difference on ACER values of 2015 and 2016, whereas the value of arithmetic (0,202) < t table (4,303) with significance value ? 0,04 <0,05. The implementation of Prolanis in 2015 (ACER = Rp. 1.095,97) seemed to be more cost effective than in 2015 (ACER = Rp. 1.268,96). Cost of biguanida drugs is the most influential factor affecting the cost-effectiveness values of Prolanis implementation in patients with type 2 DM in 2015 and 2016.
Semuel Piter Irab, Rosmin Tingginehe, Yacob Ruru
Jurnal Sains dan Kesehatan, Volume 4, pp 36-47; https://doi.org/10.25026/jsk.v4i1.1095

Abstract:
Corona Virus disease – (COVID-19) adalah penyakit infeksi yang ditemukan bulan desember 2019 di Kota Wuhan, China. COVID-19 merupakan golongan virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Akibat gangguan sistem pernapasan, gejala ringan, flu, infeksi paru-paru, dan menyerupai penyakit pneumonia. Tujuan penelitian ini untuk menganalisis dampak social distancing dan lockdown pada keterbatasan pangan balita perkotaan dan pedesaan. Metode Cross-sectional digunakan pada analisis keterbatasan pangan balita perkotaan dan pedesaan masa pandemi COVID-19 Provinsi Papua yang dilakukan Maret – Juli 2020. Tempat penelitian di Kabupaten/kota Jayapura dan Kabupaten Jayawijaya, mewakili semua Kabupaten di Provinsi Papua. Populasi seluruh balita, sampel balita di perkotaan dan pedesaan. Analisis data mengunakan independent samples t-test. Hasil penelitian menunjukkan bahwa ada perbedaan pandemi COVID-19 perkotaan dan pedesaan (p-value = 0,012), transportasi bahan makanan perkotaan dan pedesaan (p-value < 0,001), pekerjaan kepala keluarga perkotaan dan pedesaan (p-value = 0,002), pendapatan kepala keluarga perkotaan dan pedesaan (p-value = 0,004), sumber vitamin mineral perkotaan dan pedesaan ( p-value < 0,001), sumber protein (10 – 15%) perkotaan dan pedesaan (p-value < 0,001), sumber karbohidrat (60-75%) perkotaan dan pedesaan (p-value = 0,028), sumber lemak (10-20%) perkotaan dan pedesaan (p-value = 0,019), sumber energi (1250-1750 kkal) perkotaan dan pedesaan (p-value < 0,001). Tidak ada perbedaan bantuan Pemerintah perkotaan dan pedesaan pada pandemi COVID-19 Provinsi Papua (p-value = 0,564). Dapat disimpulan bahwa pembatasan status sosial ekonomi pada masa pandemic COVID-19, berdampak pada keterbatasan pangan balita perkotaan dan pedesaan Provinsi Papua. Balita perkotaan dan perdesaan mengkonsumsi makanan jumlah dan sumber zat gizi berbeda.
, Faradiba Maharani
Jurnal Sains dan Kesehatan, Volume 4, pp 99-104; https://doi.org/10.25026/jsk.v4i1.912

Abstract:
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, causes health problems and endemic in several countries. The number of new cases of leprosy is constantly reported in endemic countries. Therapeutic efforts in leprosy patients are carried out with the aim of reducing the level of transmission and disability of leprosy patients. Leprosy therapy with the use of a multidrug regimen (MDT) has been shown to be able to reduce the number of leprosy cases but has not been able to suppress the rate of growth of new leprosy cases. The constant number of new cases of leprosy in endemic areas indicates community infection and the inability of MDT as a single strategy to complete treatment and stop the transmission of leprosy. The transmission of leprosy is known to be multifactorial involving: microbial factors, host factors, and environmental factors. These factors are thought to cause immune dysregulation and increase the risk of leprosy infection in people living in endemic areas. An understanding of immune dysregulation is needed to achieve succesful treatment and the eradication of leprosy.
Yuliawati Yuliawati, Rofifah Dhia Savira, Diah Tri Utami
Jurnal Sains dan Kesehatan, Volume 4, pp 1-9; https://doi.org/10.25026/jsk.v4i1.871

Abstract:
Tonic is a substance that can increase the bodys defense system. The stimulant effect that is intertwined with the tonic effect is carried out by the central nervous system. Pecut kuda leaf and bases are useful as stimulants and tonics. This research aims to determine the tonicum effect of ethanolic extract pecut kuda leaf in mice. This was an experimental study with completely randomized group design, using male white mice and divided into five namely two control groups (K- given Na CMC 0,5% and K+ given 13 mg caffeine) and three treatment groups (ethanolic axtract of pecut kuda with a dose 50, 100 and 200 mg/kgBW) and each treatment group was repeated 5 times. The methods used were natatory exhaustion test, hanging test and sleep induction test for the parameters observed were the mice'defense on the surface of the water, the duration of the mice endurance on the hanging device and the time the mice fell asleep.The results of the observation data using Duncan's One Way ANNOVA test. The results showed that the pecut kuda leaf extract was effective against the tonic effect test at doses of 50, 100, 200 mg/kgBW. It can be said that pecut kuda leaf extract at a dose of 200 mg/kgBW has almost the same effect as K+ (13mg caffeine).
Fajar Nugraha, Pratiwi Apridamayanti, Hadi Kurniawan, Inarah Fajriaty, Siti Nani Nurbaeti, Liza Pratiwi, Safrilla Anggraeni
Jurnal Sains dan Kesehatan, Volume 3, pp 846-852; https://doi.org/10.25026/jsk.v3i6.791

Abstract:
Penggunaan buah pisang dan nanas yang banyak untuk berbagai olahan makanan akan menghasilkan penumpukan limbah kulit. Limbah kulit pisang dan nanas diketahui mengandung unsur kalium yang dapat diolah kembali untuk menjadi produk yang bermanfaat. Oleh karena itu, penelitian ini dilakukan untuk melihat kadar kalium terhadap ekstrak kombinasi kulit pisang dan kulit nanas dengan menggunakan spektrofotometer serapan atom. Metode: pembuatan ekstrak kental dilakukan dengan metode infundasi atau infusa yang dikeringkan. Ekstrak kental didestruksi dengan cara pengabuan menggunakan tanur. Kemudian dilakukan pengujian kadar kalium menggunakan spektrofotometer serapan atom pada panjang gelombang 766,5 nm. Hasil penelitian menunjukkan kalium pada ekstrak kental didapatkan sebanyak 47,483 mg/g ekstrak. Kesimpulan: ekstrak kombinasi kulit pisang dan kulit nanas mengandung kalium yang berpotensi dalam menunjang kebutuhan kalium di dalam tubuh.
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