Refine Search

New Search

Results in Journal Annals of Dermatological Research: 19

(searched for: journal_id:(3334118))
Page of 1
Articles per Page
by
Show export options
  Select all
Tao Kan, Guo Lili, Fernandez Jose, Webb Corey, Liu Junfeng, Hu Xincheng, Dan Yang Dan Yang,
Annals of Dermatological Research, Volume 5, pp 022-029; https://doi.org/10.29328/journal.adr.1001018

Abstract:
Background: The plant Artemisia annua has been used in traditional Chinese medicine for many years. Rich in bioactive molecules, the A. annua plant is used to extract the anti-malaria compound artemisinin (< 1%), which results in most of the plant being unutilized. One byproduct of artemisinin extraction is artemisia naphtha (AN), which has yet to be studied extensively. Aims: Study the activity of a novel AN oil extract against microbes, pro-inflammatory cytokines, and dermatological endpoints that are key for eczema and acne pathogenesis to determine if an effective A. annua extract for these skin conditions can be developed. Methods: Gas chromatography-mass spectrometry was performed to determine the composition of AN oil. P. acnes, S. aureus, M. furfur, and C. albicans were cultured to determine minimal inhibitory concentration. in vitro studies utilizing keratinocytes and macrophages were treated with AN oil and gene expression measured by quantitative RT-PCR. A 13-subject clinical trial was performed with 1% AN oil Gel to assess its potential benefits for sensitive and acne prone skin. Results: AN oil upregulates filaggrin gene expression and possesses antimicrobial and anti-inflammatory activity inhibiting LPS, S. aureus and "Th2 induced" pro-inflammatory mediator release (IL-6, IL-8 and TSLP). Clinical assessment of 1% AN Gel shows it reduces acne blemishes and the appearance of redness. Conclusion: Previously an underutilized and unpurified byproduct, AN is now the source to develop the first topical AN oil for cosmetic use with an activity profile that suggests it is effective for those with sensitive and/or acne prone skin.
, S Mansouri, S Sialiti, B Hassam
Annals of Dermatological Research, Volume 5, pp 020-021; https://doi.org/10.29328/journal.adr.1001017

Abstract:
Follicular psoriasis is an uncommon diagnosis and probably the least well-known subtype of psoriasis. Hence, we report the clinical and histological findings of follicular psoriasis in one patient to raise awareness of this rare entity.
, Gassama Mamadou, Gassama Aboubakar Hemedi, Dicko Adama, Sanogo Hawa, Tenin Karambe, Traoré Chata, Diakité Mamourou, Koné Chaka, Dao Sounkalo, et al.
Annals of Dermatological Research, Volume 5, pp 013-017; https://doi.org/10.29328/journal.adr.1001015

Annals of Dermatological Research, Volume 5, pp 006-012; https://doi.org/10.29328/journal.adr.1001014

Abstract:
When grouping children with psoriasis depending on TaqI (T/C) genotypes of the VDR gene, the youngest age of disease onset and the longest duration of dermatitis (5.60 ± 0.77 years and 4.90 ± 0.68 years, respectively) showed up in case of the CC genotype. In case of the TT genotype, disease onset coincided with an older age, and the history of present illness was the shortest (10.26 ± 0.64 years and 2.59 ± 0.58 years, respectively). PASI (20.32 ± 3.43) and BSA (40.00 ± 6.11) severity indices were the highest and of statistically significant difference to those in other groups in the presence of the CC genotype. In case of the TC genotype, the index PGA (2.80 ± 0.15) was the lowest and made a statistically significant difference to the values of other groups. A negative correlation between vitamin D levels and the PASI, PGA, BSA was identified in children holding CC and TC genotypes. Conclusion: The clinical presentation of dermatitis and its epidemiological features in children with psoriasis, namely the age of disease onset, duration of exacerbation, body surface area and the intensity of psoriasis symptoms depend on vitamin D serum levels and genotypes of the TaqI polymorphic variant of the VDR gene.
, Mahave Idoia González, Oribe Irene Vidal, del Pozo Gil Mª Dolores, Díaz Mónica Venturini, Labairu Teófilo Lobera
Annals of Dermatological Research, Volume 4, pp 014-016; https://doi.org/10.29328/journal.adr.1001012

Abstract:
Ranitidine is a widely used drug in Europe and its intake is usually well tolerated. Hypersensitivity reactions due to ranitidine are uncommon. The immediate mild reactions type are the most prevalent. In some special cases a delayed type reaction such as contact dermatitis or severe reactions with systemic involvement have been reported. In the present paper, a case report of a 78-year old patient who experienced a maculopapular eruption after 7 days of oral treatment with ranitidine is described. Patch tests were performed twice with ranitidine with positive results confirming the diagnosis. In order to discard a double sensitization and a possible cross-reactivity phenomenon, patch test was performed once with famotidine, with a negative result. This is the first maculopapular exanthema reported as type IV hypersensitivity reaction to ranitidine confirmed by patch testing. Moreover, there are only two reported cases showing a double sensitization to ranitidine and to other H2-receptor antagonists by patch testing after a delayed reaction due to ranitidine, the other being H2-receptor antagonists involving cimetidine and nizatidine, not famotidine.
, Frikh Rachid, Hjira Naoufal, Boui Mohammed
Annals of Dermatological Research, Volume 4, pp 006-008; https://doi.org/10.29328/journal.adr.1001010

Abstract:
Bee venom is a very rich and varied biochemical complex, which explains the multitude of its physiological effects as well as its medical indications. In dermatology, apart from psoriasis, few studies have been conducted concerning its interest and effectiveness; however the preliminary results remain so promising and encouraging. We present a clinical case illustrating the efficacy of bee venom in cutaneous varicosities, with a review of the literature of its main dermatological indications.
Coulibaly Yaya Ibrahim, , Keita Modibo, Dolo Housseini, Sangaré Modibo, Fomba Abdoulaye, Kodio Mamoudou, Diarra Nouhou, Sidibé Mamadou, Maiga Oumar, et al.
Annals of Dermatological Research, Volume 4, pp 001-005; https://doi.org/10.29328/journal.adr.1001009

, Bay H Bay, Dassouli R, Jouari O El, Lamouaffaq A, Douhi Z, Elloudi S, Mernissi Fz
Annals of Dermatological Research, Volume 2, pp 008-011; https://doi.org/10.29328/journal.adr.1001005

Page of 1
Articles per Page
by
Show export options
  Select all
Back to Top Top