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Tushar Kulkarni, Khaled El-Atawi,
Journal of Pediatrics & Neonatal Care, Volume 11, pp 23-25; doi:10.15406/jpnc.2021.11.00437

We report a case of a neonate who was diagnosed to have intracardiac mass as a fetus and presented with white linear papules that was diagnosed to be Linear Verrucous Epidermal Nevus. Apart from the intracardiac mass, most likely rhabdomyoma, MRI Brain also showed presence of tubers and the Next Generation Sequence Analysis confirmed the diagnosis of Neonatal Tuberous Sclerosis. The neonate remained asymptomatic and was discharged home and remains under close follow up without any symptoms. It is thus suggested that Linear Verrucous Epidermal Nevus, a cutaneous manifestation not described with Tuberous Sclerosis could be considered under the ever-expanding cutaneous signs of Tuberous Sclerosis and should alert the physician toward its possibility.
Irina Ostroukhova, Olga Rudko, Artemii Tretiakov
Journal of Neurology & Stroke, Volume 11, pp 37-39; doi:10.15406/jnsk.2021.11.00452

Migraine is diagnosed in approximately 15% of the population in the developed countries. This disease affects not only patient’s well-being, but also economy and social sphere. Despite this significant impact, little is known on the genetic causes of migraine. Several migraine symptoms, including tiredness, yawning, drowsiness, and the desire to eat certain foods, give an idea of migraine connection to orexin system. This system includes orexines – peptides, predominantly synthesized in the lateral hypothalamic area and involved in wake and sleep cycle and many other neurological functions; and their two receptors HCRTR1 and HCRTR2. Here we summarize known data on orexin system polymorphisms and changes in peptide concentration in patients with migraine.
Jang Bahadur Prasad, Pradyuman Verma, Naresh K Tyagi
Journal of Cancer Prevention & Current Research, Volume 12, pp 36-42; doi:10.15406/jcpcr.2021.12.00451

Hematology & Transfusion International Journal, Volume 9, pp 21-26; doi:10.15406/htij.2021.09.00246

Evaluation of immunoprofile as predictive and prognostic biomarker are essential to follow up patients in Multiple Myeloma after autologous hematopoietic stem cells transplantation (AHSCT). It can be defining the engraftment and predicts complications. An AHSCT was performed for the first time in the United Arab Emirates to treat a patient with multiple myeloma. We apply the evaluation of the patient's immune status before and during the early follow-up by flow and mass cytometry. The analysis revealed a decrease in all leukocyte populations in blood seven days after transplantation, mainly of B and T helper lymphocytes. The patients showed diarrhea and cellulitis as complications. An increase in regulatory T and NK lymphocytes was evidenced at the same time. 28 days’ post-transplantation, all lymphocyte populations were recovered, except for B lymphocytes, a high level of T regulatory and NK was maintained. The early immune restoration coincided with the recovery of the complications presented by the patient. the leukocyte composition of apheresis was similar to that found in blood at baseline time. Our study evidenced that the extended immunoprofile by mass cytometry could be useful to predict the outcome and response to transplantation.
Belén Matías-García, Ana Sánchez-Gollarte, Ana Quiroga-Valcárcel, Fernando Mendoza-Moreno, Javier Mínguez-García, Cristina Vera-Mansilla, Manuel Díez-Alonso, Inmaculada Lasa-Unzué, Alberto Gutiérrez-Calvo
Published: 15 March 2021
MOJ Surgery, Volume 9, pp 35-38; doi:10.15406/mojs.2021.09.00189

Introduction: COVID-19 infection has spread throughout the world and is considered a pandemic. Since its appearance, the number of non-COVID-19 patients admitted to hospitals has decreased and patients differ care for emergency diseases. We analyze the impact of the SARS-CoV-2 coronavirus pandemic on the management of acute cholecystitis. Material and methods: Retrospective observational study that includes all patients diagnosed with acute cholecystitis during the SARS-CoV-2 coronavirus pandemic (period between March 11th and June 21st, 2020) and patients diagnosed with acute cholecystitis in the same period, the previous year in our center. Patient’s features, management, postoperative complications and mean hospital stay were compared. Results: In 2020, 19 patients with acute cholecystitis were diagnosed compared to 21 who were registered in the same period in 2019. The mean number of days from symptoms onset in 2020 was 2.42±1.8 days, while in 2019 it was 3.5±3.1 days (p=0.32). The percentage of cholecystectomies, percutaneous cholecystostomies and conservative management was similar in both periods. Among patients who underwent cholecystectomy in 2020, 37.5% had no complications, 62.5% had accidental opening of the gallbladder, and none had bleeding. Among patients who underwent cholecystectomy in 2019, 81.8% had no complications, 9.09% had accidental opening of the gallbladder, and 9.09% presented bleeding. The mean stay in 2020 was 4.21±3.2 days, compared to 8.57±7.4 days in 2019 (p=0.005). Two patients of 19 diagnosed with acute cholecystitis in 2020 had COVID-19 disease. Conclusion: The mean stay of the patients was shorter in 2020 period. These results can be explained by an early surgical management. So, early laparoscopic cholecystectomy should be considered as a treatment for acute cholecystitis in COVID-19 times if the clinical and hospital situation allows it. We found no differences in the number of patients diagnosed with acute cholecystitis between the two periods, nor in the mean number of days from the onset of symptoms.
Marjan Dzeparoski
Pharmacy & Pharmacology International Journal, Volume 9, pp 27-28; doi:10.15406/ppij.2021.09.00322

J Belkhair, I Karrati, M Tarmidi, M El Mezouari, R Moutaj
Journal of Microbiology & Experimentation, Volume 9, pp 29-32; doi:10.15406/jmen.2021.09.00319

Huang Wei Ling
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00551

Introduction: Breast cancer is the most common cancer-affecting women worldwide. Western current perspectives are starting to comprehend cancer as a systemic disease from the start. In TCM, the formation of cancer is associated energy deficiencies with Heat retention. Spleen deficiency is one of the major causes of formation of Phlegm leading to the formation of tumors. There are studies associating the five elements in TCM with chakras’ energy centers and measuring the chakra, the author will be measuring the internal massive organs energy. Purpose: To demonstrate that there is chakras’ energy deficiencies chronically present in the body of the patient with breast cancer. Also, to analyze the importance of treating the subject systemically, through the replenishment of chakras’ energy centers. Methods: two cases report, both were female patients (42 and 56years old), with the diagnosis stress and anxiety in the first and the second with diagnosis of sub retinal fluid retention, both patients with past history of breast cancer twenty and six years ago, removed with surgery. Chakras’ energy measurement through radiesthesia procedure was done. Results: all the chakras were in the lowest level of energy, rated in one out of eight. Conclusion: patients with history of breast cancer have chakras’ energy centers deficient in energy and the replenishment of these chakras is the major importance to prevent future formation of metastasis, new cancer in other sites or the formation of any chronic diseases.
Yuri V Sergeev, Annapurna Kuppa
Journal of Analytical & Pharmaceutical Research, Volume 10, pp 41-48; doi:10.15406/japlr.2021.10.00364

Usher syndrome type 1B (USH1B) is a genetic disorder caused by mutations in the unconventional Myosin VIIa (MYO7A) protein. USH1B is characterized by hearing loss due to abnormalities in the inner ear and vision loss due to retinitis pigmentosa. Here, we present the model of human MYO7A homodimer, built using homology modeling, and refined using 5 ns molecular dynamics in water. Global computational mutagenesis was applied to evaluate the effect of missense mutations that are critical for maintaining protein structure and stability of MYO7A in inherited eye disease. We found that 43.26% (77 out of 178 in HGMD) and 41.9% (221 out of 528 in ClinVar) of the disease-related missense mutations were associated with higher protein structure destabilizing effects. Overall, most mutations destabilizing the MYO7A protein were found to associate with USH1 and USH1B. Particularly, motor domain and MyTH4 domains were found to be most susceptible to mutations causing the USH1B phenotype. Our work contributes to the understanding of inherited disease from the atomic level of protein structure and analysis of the impact of genetic mutations on protein stability and genotype-to-phenotype relationships in human disease.
Alexis Svokos, Kendall Cunningham, Maranda Sullivan Do, Saif Ahmed
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00550

We present the case of a 26-year-old female who experienced secondary postpartum hemorrhage nine days after an uncomplicated elective repeat low transverse cesarean section. She was found to have a uterine pseudoaneurysm and underwent gel foam embolization of the right uterine artery. Subsequently, patient was diagnosed with pulmonary embolism on post-embolization day 3, and was initiated on anti-coagulation regimen.
Ingrid Nascimento dos Santos, Matheus Mychael Mazzaro Conchy
International Journal of Family & Community Medicine, Volume 5, pp 31-37; doi:10.15406/ijfcm.2021.05.00218

The present work has as its study the analysis of public policies, regarding access to the right to public health, as well as the difficulties, the neglect of the provision and the length of the concession. The difficult way for doctors to exercise their profession, excessive shifts, lack of specialists, medicines and beds, lack of fair remuneration and various problems; the analysis of the judicialization of public health and the institutes that medicine calls: Euthanasia, Orthothanasia, Dysthanasia and Mistanasia. The methodology used was the tool: bibliographic. At the end of this article, there will be an examination of the studies analysed, and the effectiveness of the judicialization of public health.
José Efraín Ramírez-Benítez, Norma Laura Rodríguez-Ávila, , Ángel Virgilio Domínguez May, Héctor Octavio Guerrero Turriza, Jorge Román Herrera-Flores, Abigail Malerva Díaz
Horticulture International Journal, Volume 5, pp 43-49; doi:10.15406/hij.2021.05.00202

Karp Im
International Journal of Biosensors & Bioelectronics, Volume 7, pp 25-28; doi:10.15406/ijbsbe.2021.07.00207

Mark R Burge, Imaneh Fallahi, Madhavi Garimella, Steve Mitchell
Journal of Diabetes, Metabolic Disorders & Control, Volume 8, pp 31-36; doi:10.15406/jdmdc.2021.08.00218

Background: Insulin detemir is long-acting insulin analog that is weight-neutral compared with other long-acting insulins in patients with type 1 diabetes. One mechanism for this may be an effect of insulin detemir to enhance satiety. We hypothesized that type 1 diabetes patients on insulin detemir will eat fewer calories when presented with a standardized buffet meal following a 24-hour fast as compared to those on insulin glargine. Methods: Ten subjects with C-peptide negative type 1 diabetes participated in a randomized, double-blind crossover study in which they received equivalent doses of either insulin detemir or insulin glargine twice daily for at least 3 weeks. They were subsequently admitted to the UNM Clinical Research Unit for a 24-hour fast, after which they were allowed to eat to satiety from a standardized buffet. Caloric consumption, hunger score and body compositions were measured. Leptin, Ghrelin and Peptide YY were assessed at baseline, after 24-hour fast, and after ingestion of the meal. Results: Subjects were aged 35±11 years, had diabetes for 18±11 years, had A1c levels of 8±1% and BMI of 30±8 kg/m2. Short acting insulin doses were higher for subjects receiving insulin detemir versus insulin glargine (p<0.001). Hunger scores, total energy ingested following the 24-hour fast, and Resting Energy Expenditure did not significant differ between the two study conditions. Conclusion: The weight-neutrality of insulin detemir in type 1 diabetes is not attributable to reduced caloric intake following a fast, or to serum satiety factors.
Vasquez L, Rivera G, Miranda Y, Soto C, Cevallos P, Rodriguez I, Couto R, Crespo D
Journal of Microbiology & Experimentation, Volume 9, pp 9-13; doi:10.15406/jmen.2021.09.00316

Gichuru Stephen Mwangi, John-Paul Ogalo, Thomas Mutua Kedera
Published: 24 February 2021
MOJ Surgery, Volume 9, pp 28-33; doi:10.15406/mojs.2021.09.00188

Anil Heroor, Tejas Savdekar, Prashant Dhanke, Aysha Khan, Akshay Patil, Hitesh Rajendra Singhavi
Published: 23 February 2021
MOJ Surgery, Volume 9, pp 21-26; doi:10.15406/mojs.2021.09.00187

Fawzia Mohamed Afrid Butt, Symon Wangombe Guthua
Published: 23 February 2021
MOJ Surgery, Volume 9, pp 15-19; doi:10.15406/mojs.2021.09.00186

Rogelio Edgar Castillo-Ramírez
International Journal of Family & Community Medicine, Volume 5, pp 27-29; doi:10.15406/ijfcm.2021.05.00217

In December 2019, in Wuhan (Hubei, China), a novel severe acute respiratory syndrome coronavirus could be identified (SARS-CoV-2). The need of home isolation to avoid getting the infection and to avoid its spread, have been associated with fear and other psychological consequences in population of affected countries. Music has demonstrated its positive complementary effect in management and improvement of anxiety, depression, pain and other clinical and social situations associated with negative effects in well-being and quality of life. To date, there are no clinical trials that examine directly the relation between music interventions and improvement of negative emotions for people in quarantine but based on previous research we know that it could be employed as an innocuous and safe complementary intervention to help people to alleviate these feelings. Since the pandemic was declared, musicians have taken different instruments and have even used their own voice to play live music from their balconies or even in the street, showing their solidarity and attempts to encourage their neighbors and other people nearby not to give up against COVID-19.
Ahmed Mehanna, Moataz Hendawy
Journal of Analytical & Pharmaceutical Research, Volume 10, pp 26-39; doi:10.15406/japlr.2021.10.00363

Dipeptidyl peptidase-4 (DPP-4) is a relatively new target for the treatment of type-2 diabetes mellitus (T2DM). Most of the inhibitors designed to date have not relied on modelling studies to guide their lead optimization efforts. In our previous work, we designed compounds that retain the (R)-3-amino-4-(2,4,5-trifluorophenyl)butanamido S1-pocket binding moiety of sitagliptin, but have S2-pocket binding moieties that are more hydrophobic than the triazolopiperazine. In an effort to understand how Vina docking algorithm can be integrated in discovering new inhibitors of DPP-4; we designed, synthesized and evaluated new compounds that vary in the hydrophobic properties of the S2-pocket binding groups. Our results indicate that the minimum binding energy predicted from the docking studies was not reliable in designing more active candidates. However, visualizing the binding modes of each compound and modifying it to target neighboring key residues in the active site is a more effective implementation of the docking in the design of new compounds. Compounds in this study displayed IC50 values ranging from 0.37 µM to 11 µM.
M Pavlichenko, N Kosovtsova, N Bashmakova
Journal of Pediatrics & Neonatal Care, Volume 11, pp 7-13; doi:10.15406/jpnc.2021.11.00434

Introduction: The leading cause of chronic renal failure in newborns, which occurs soon after birth is obstructive uropathies. Objectives: To prove the effectiveness of nephroamniotic shunting based on the evaluation of perinatal outcomes of this procedure, as well as a comparative analysis of the use of the stent manufactured by "Cook" (Ireland), 3.0 Fr/100 mm and the stent “SDE–MED”, 3.0 Fr/50 mm with the original shape of pigtails. Methods: After checking the safety of the stent “SDE-MED”, 3.0 Fr/50 mm developed by FGBU Mother and Child Care Research Institute with the original shape of pigtails in an animal experiment, the stent was used in clinical practice for intrauterine shunting in cases of unilateral or bilateral hydronephrosis of grade III to IV and posterior urethral valve disorder. In the final part of the study, a comparison of the outcomes of nephroamniotic shunting using two different stents was made. Results: The “SDE–MED” 3.0 Fr/50 mm stent provided more effective fixation in the fetal kidney cavity system in comparison to the stent manufactured by “Cook” (Ireland) 3.0 Fr/100 mm. Conclusion: Intrauterine shunting surgery of the upper urinary tract is a pathogenetically justified method of treating urinary tract obstructions and can be used to correct all types of fetal renal obstructions.
Soika Alexander Kuzmich
Physics & Astronomy International Journal, Volume 5, pp 6-9; doi:10.15406/paij.2021.05.00228

This work is a continuation of the author's studies,1,2,3 related to the elucidation of the physical nature of dark sunspots. They showed that the appearance of cold sunspots, the temperature of which is below the temperature of the photosphere, is incompatible with the second law of thermodynamics. Sunspots in the Sun's photosphere can only be hot. This article provides a thermodynamic analysis of the work of the Sun as a heat engine. It is shown that sunspots are dissipative structures that spontaneously appear in the photosphere of the Sun and ensure its viability as a source of optical radiation. Sunspots play the role of a cooler for the sun's global heat engine, and without them its radiant glow would be impossible, just like the operation of any heat engine without a cold heat sink. In addition, it is shown that all the phenomena of solar activity are caused by the operation of the photospheric heat engine of the Sun, in which sunspots are the source of heat.
Seham I Al-Nafea, Mohammed O Aljahdali
Journal of Applied Biotechnology & Bioengineering, Volume 8, pp 16-22; doi:10.15406/jabb.2021.08.00246

The protective actions of ethanol Alhagi maurorum (AM) root ethanol extract on acetaminophen-induced oxidative stress and renal toxicity in mice was evaluated. Forty male SWR strain albino mice aged 8 weeks were grouped into five groups. G1 (n=5): as control. G2 (n=5): administered orally a single dose of acetaminophen (2000mg/kg). G3 (n=10) administrated orally 200 mg/kg of roots ethanol extract for one week then acetaminophen as G2 at 8th day and; G4 (n=10) administrated orally 400 mg/kg of roots ethanol extract for one week then acetaminophen as G2 at 8th day; G5 (n=10) administrated orally 600 mg/kg of roots ethanol extract for one week then acetaminophen as G2 at 8th day. At end of experiments, the mice were killed under anesthesia and blood samples were gathered to preform complete blood test (CBC), serum levels of urea and creatinine and oxidative stress biomarkers as superoxide dismutase (SOD), glutathione (GSH), and catalase (CAT) using available Elisa mice kits. Kidneys were removed and histologically examined. Acetaminophen intake significantly elevated WBCs, neutrophils, monocytes, urea and creatinine levels and significantly decreased RBCs, hemoglobin, hematocrit, GSH, SOD and CAT (P
Maria Goretti M G Penido, Celina F Rezende, André S Alvarenga, Mariângela L Cherchiglia, Viviane L Nery
Urology & Nephrology Open Access Journal, Volume 9, pp 6-10; doi:10.15406/unoaj.2021.09.00300

Introduction: Pediatric chronic kidney disease interferes with weight growth, psychosocial status, and also affects quality of life. Objectives: To outline the clinical, epidemiological, social and economic profile of children and adolescents undergoing renal replacement therapy (RRT) at Santa Casa de Belo Horizonte, Minas Gerais - Brazil. Methods: Observational and cross-sectional study. 82 children and adolescents from 0 to 17yrs of age who had undergone RRT with at least three months of registration were included. Patients who died in the first three months on RRT, acute patients, and those older then 18yrs were excluded. Anthropometric analysis was performed and qualitative variables were expressed in absolute frequencies and percentage. Results: 63.5% were male; median age of 9.25yrs at the beginning of RRT. 57% were short, and the BMI was normal in 88%. 82% were followed by nephrologists before RRT, 64.5% had residual diuresis. Hemodialysis was the main initial modality of RRT. Long-term double-lumen catheter was the most widely used vascular access. 85% of those who were at school age were attending school. Most patients lived in the countryside, used public transport, and had a low per capita income. SUS (Health Unic System) was the paying source and were registered at UBS (Basic Health Unity). The mother was the caregiver in 80.5%, 36.6% had glomerulopathy and 26.8% CAKUT uropathy. Sepsis was the main cause of death. 34 patients were transplanted. Discussion and Conclusion: To know the clinical, epidemiological, social, and economic profile of pediatric patients in RRT is important in order to increase the chances of successful treatment and a better quality of life.
Hannah O Akinrotohun, Ayobami O Oyedele, Oluwatoyin A Igbeneghu, Lara O Orafidiya
Journal of Analytical & Pharmaceutical Research, Volume 10, pp 14-24; doi:10.15406/japlr.2021.10.00362

The aims of this study were to determine the emulsifying properties of Theobroma cacao pod husk ash (CPHA) methanolic extract combined with shea butter and explore the antibacterial activities and physicochemical characteristics of resulting emulsions toward the development of a topical antibacterial lotion formulation for shaving bumps treatment. The ash resulting from combustion of pod husks of freshly harvested ripe cocoa fruits was extracted with methanol and the extract evaporated to dryness. Shea butter was also extracted by traditional method from kernels from the shea tree. These natural-source materials were combined with pharmaceutical ingredients (buffer, viscosity enhancer, preservative) to develop fluid emulsion formulations. Stability characteristics (droplet size, viscosity, creaming, and pH) of the formulations were evaluated as well as their antibacterial activities against microorganisms isolated from after-shave bump swabs of adult male volunteers and against reference organisms; in order to select product(s) of best qualities suitable as shaving bumps medication. The prototype formulations exhibited suitable physicochemical properties and demonstrated inhibitory activities against several isolated shaving bump microbes and the reference organisms namely, Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa. Two formulations were finally selected as having physicochemical and antibacterial qualities most suitable for shaving bumps therapy, which contained shea butter (20%), citrate buffer (5%), and parabens (0.3%), prepared using 5% CPHA extract solution with and without methyl cellulose (2%), respectively. The novel shea butter-incorporated emulsion-lotion formulations of CPHA extract provide a useful therapeutic option of topical medication for the treatment of shaving bumps in men.
Rander Junior Rosa, Debora Nascimento da Nobrega
Pharmacy & Pharmacology International Journal, Volume 9, pp 17-21; doi:10.15406/ppij.2021.09.00320

Hayriye Alp
Published: 11 February 2021
MOJ Surgery, Volume 9, pp 7-9; doi:10.15406/mojs.2021.09.00184

Tina M Penhollow, Luis Torres, Marcelo Henrique Ferreira, Mauriceia Cassol, Bruno Francisco de Fraga, Jade Zaccarias Bello, Sheila Tamanini de Almeida
International Physical Medicine & Rehabilitation Journal, Volume 6, pp 19-20; doi:10.15406/ipmrj.2021.06.00273

Ayser Al-Mshhdani, Claudia Payá Ten, Facog Justin To Md
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00549

Background: Meigs’ syndrome is the triad of ovarian neoplasm, ascites and pleural effusion, while Pseudo-Meigs’ syndrome is the presence of ascites and pleural effusion with other pelvic tumors. Ascites resolves after tumor resection. Our case does not meet classic criteria for either but is likely a variant of Pseudo-Meigs’ syndrome. Case: A 30-year-old female had multiple Emergency Department visits for abdominal pain, distention, and shortness of breath. Imaging showed severe abdominal ascites with a large leiomyomatous uterus but no pleural effusions. Multiple paracenteses revealed benign cytology. After counselling, she underwent an abdominal myomectomy which resolved her recurrent ascites. Conclusion: Variants of Pseudo-Meigs’ syndrome should be considered in the differential of abdominal pain and leiomyomas with ascites, and surgical management should be offered.
Lucas Silva
International Journal of Family & Community Medicine, Volume 5, pp 23-25; doi:10.15406/ijfcm.2021.05.00216

Marcelo Henrique Ferreira, Mauriceia Cassol, Bruno Francisco de Fraga, Jade Zaccarias Bello, Sheila Tamanini de Almeida
International Physical Medicine & Rehabilitation Journal, Volume 6, pp 22-25; doi:10.15406/ipmrj.2021.06.00274

Kulvinder Kochar Kaur, Gautam Allahbadia, Mandeep Singh
Journal of Diabetes, Metabolic Disorders & Control, Volume 8, pp 6-25; doi:10.15406/jdmdc.2021.08.00216

Bastidas Gilberto, Bastidas Daniel, Bastidas-Delgado Geraldine
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00548

In pregnant women, parasitic diseases constitute an important public health problem due to physiological factors that characterize this stage. That is why it is crucial to review different aspects of the parasite-host interaction as tools for the prevention and control of these pathologies during pregnancy, the objective of this paper. This is a documentary-type investigation. The information obtained was grouped into 6 chapters: resistance or susceptibility of pregnant women to parasitic diseases, anemia and parasitic diseases in pregnant women, relationship between micronutrient deficiency and parasite infection in pregnant women, congenital transmission of parasites, treatment of some parasitosis in pregnant, and conclusions.
Urvashi Verma
International Journal of Family & Community Medicine, Volume 5, pp 19-21; doi:10.15406/ijfcm.2021.05.00215

Daschievici Luiza, Ghelase Daniela
International Robotics & Automation Journal, Volume 7, pp 14-16; doi:10.15406/iratj.2021.07.00220

Othmar W Winkler
Biometrics & Biostatistics International Journal, Volume 10, pp 1-2; doi:10.15406/bbij.2021.10.00324

This study explores the correlation between two variables and to demonstrate a simple graphic method to assess their degree of correlation. Following the lead of early English biometricians, it has been tacitly assumed that the studied variables develop in the same direction: when variable A’s measurements are higher from one object to another, the measurements of variable B, also are higher. The customary measure of co-relation relies on a least squares fitted trend line, then assuming that the trend is more real than, and has priority over the individually recorded data. The situation changes when measurements of variables develop in opposite directions: The very first data set I used to perform a correlation analysis was a study of student grades achieved and the percentage of their having missed classes: the more a student was absent from class, the lower were his achieved grades. In that situation the accepted model of correlation analysis – the mathematically fitted straight line and the squared distance of each student’s record from that line - was not appropriate. The usual correlation coefficient contradicted visual evidence of those data because the model underlying that situation treats the individual data as having more reality value than the general trend, but not as deviations or errors. The visual appearance, the graph of that situation, resembles a rectangular triangle, formed by the horizontal and vertical axis as its catheters, and the hypotenuse formed by a line through and representing the highest data points. This image justifies the expression “Triangular correlation”.
Amr S Soliman, Saad Alshahrani Md, Robert M Chamberlain, Ahmed Hablas, Steven Remmenga, Jane L Meza, Ibrahim A Seifeldin, Mohamed Ramadan, Mariah Murray Mph
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00547

Background: Uterine cancer is one of the common women’s cancers worldwide. There are significant variations in uterine cancer incidence rates globally and the incidence in Egypt is one of the lowest. Several studies have shown that hysterectomy might be a factor in underestimating the observed incidence of uterine cancer. However, no studies have been conducted in Egypt to examine this observation. Methods: Pathologic reports of all 1040 hysterectomy specimens examined in 2013 and 2014 in the Gharbiah province, Egypt were abstracted. Prevalence of hysterectomy was estimated and used for adjusting the incidence rate of uterine cancer in the Gharbiah population-based registry by excluding the hysterectomized women from the population at risk. Pre- and post- adjustment rates were compared and 95% confidence intervals (CIs) were calculated. Results: The prevalence of hysterectomy was estimated as 13.1 per 10,000 women, 95% CI (12.65-13.66). The prevalence of hysterectomy did not have a significant impact on uterine cancer incidence [pre-adjustment (2.78, 95% CI 2.58-3.00) and post-adjustment (2.79, 95% CI 2.58-3.00)]. Observing a significant effect of hysterectomy on underestimating the incidence of uterine cancer in this population required multiplying the observed prevalence by at least 110 times. Discussion: This study confirmed the previously documented low incidence of uterine cancer in this population of Egypt. The lack of evidence about the possible role of hysterectomy in lowering uterine cancer incidence justifies the need for additional research to identify the protective factors for uterine cancer in this population.
Didik Sumanto, Sayono Sayono, Puji Lestari Mudawamah
Journal of Microbiology & Experimentation, Volume 9, pp 1-2; doi:10.15406/jmen.2021.09.00314

Published: 3 February 2021
MOJ Gerontology & Geriatrics, Volume 6, pp 22-26; doi:10.15406/mojgg.2021.06.00262

Abigail Clarke-Sather, Michael J Weber, Kelly Cobb, Lindsay Naylor
Journal of Textile Engineering & Fashion Technology, Volume 7; doi:10.15406/jteft.2021.07.00263

Throughout the world thousands of infants are born each day according to the World Health Organization. All infants can benefit from the use of Kangaroo Care (KC) or bare skin-to-skin contact between caregiver and infant. One of the key principles to getting the most from KC is that is must be performed for at least one hour according to the World Health Organization. Yet, the duration of KC is rarely measured. This study explores the use of a simple device, a conductive thread stitch sensor coupled with a pair of magnets and a microcontroller, to measure the duration of KC automatically. For this study, a single subject used the sensor with a specific KC garment and performed KC with a weighted doll. It was determined, that when comparing manual timed values of the duration of KC to the sensor values, there was 6.43±5.67% average percentage difference. This proof of concept shows that this simple device can be used to determine the duration of KC in an effective manner.
Leelananda Rajapaksha, Dmc Champathi Gunathilake, Sm Pathirana, Tn Fernando
MOJ Food Processing & Technology, Volume 9, pp 7-16; doi:10.15406/mojfpt.2021.09.00255

In Sri Lanka, 70% of 21 million population live in non-urban areas, and agriculture provides livelihood for approximately 40% of them. The agricultural marketing process in the country is a complex operation due to services and functions involved in moving a crop product from where it was produced to where it would finally be consumed. Further, with a wide range of agricultural crops being produced, post-harvest handling process create different degrees of quantitative and qualitative losses in a complex market chain, which are estimated at 20% to 40% for vegetables and 30% - 40% for fruits. Improper and non-scientific post-harvest practices and handling, gaps in integration of cold chain practices & elements with post-harvest process, and lack of knowledge & awareness on many related aspects at grass root farmer level etc. appear to contribute to losses that finally prevent due economic benefits reaching the small-scale producer. In order to increase the effectiveness of post-harvest process handling of fruit and vegetables, appropriate corrective measures targeting small scale producers as well as commercial scale producers need to be popularized and practiced. At small scale producer level, promotion of appropriate low-cost post-harvest practices and procedures, facilitating low-cost cold chain elements and user-friendly information flow mechanism on market situation would certainly help avoid some of the steps that lead to losses. Monitoring system of commercial post-harvest handling process that ensure scientific bulk handling, storage and transportation of fruit and vegetables, properly designed economic centers with well regulated environmentcontrolled storages etc. would greatly reduce loses in bulk handling, ensuring better food security in the island.
Citlalli Harris-Valle, Marisela Ramírez- Morales, Ezequiel Mora- Guzmán, Martín Palafox- Rodríguez
Horticulture International Journal, Volume 5, pp 30-33; doi:10.15406/hij.2021.05.00199

Ivone Giffard Mena
Journal of Aquaculture & Marine Biology, Volume 10, pp 8-11; doi:10.15406/jamb.2021.10.00302

Tachibana Tomoko
International Journal of Family & Community Medicine, Volume 5, pp 15-17; doi:10.15406/ijfcm.2021.05.00214

, Hesham Goudah, Hossam Elshenoufy
Obstetrics & Gynecology International Journal, Volume 12; doi:10.15406/ogij.2021.12.00546

Background: Corona virus disease 2019 (covid 19) is a virus that affect the respiratory tract with a recently identified coronavirus emerged as a zoonotic virus that infect human. Objective: The aim of the study was to assess the level of awareness between pregnant women about the corona virus and how to deal with the coming new born, their children and relatives and their level of knowledge about symptoms and methods of prevention and to counsel them how to prevent the spread of the disease and when to seek a medical advice for better maternal, neonatal and child health. Patients and methods: A prospective descriptive study was made in the period from 25 march to 25 May 2020, 324 multigravida pregnant women who have previous living children were included into this study, every pregnant woman was asked questions in a questionnaire form to assess the women awareness regarding symptoms of covid 19 and how to prevent themselves and their children and relatives from infection with corona virus. Results: The questionnaire that was made to women attending antenatal care clinic revealed a high degree of knowledge about symptoms of covid-19, with the highest level for dyspnea (98.5%) in between tem, wile for cough 97.5% of the women knows that cough is one of its symptoms, Also 95.4% of these ladies are aware that fever is one of the alarming criteria of the disease. Conclusion: Pregnant women included in the present study have a high level of awareness regarding covid-19 symptoms and how to avoid virus transmission. We tried to increase the level of awareness between Pregnant women and their children, so we made a thorough counseling to these pregnant ladies regarding crucial points to follow during the pandemic to prevent their exposure and their children exposure to infection, when to seek medical help and how to follow up their pregnancy during the pandemic.
Pammela Araújo Lacerda, Liliane Marinho Ottoni Costa, Guilherme Cuoghi Bellato, Lucilene Lopes-Santos, , Nilva Karla Cervigne
Journal of Cancer Prevention & Current Research, Volume 12, pp 9-18; doi:10.15406/jcpcr.2021.12.00448

Daniella Spacassassi Centurion,
International Physical Medicine & Rehabilitation Journal, Volume 6, pp 16-17; doi:10.15406/ipmrj.2021.06.00272

Chao Zhou, Honghai Yang, Hua Zhou, Feina Liu, Yan Zheng, Yanhong Bi, Xin Wang, Zhanzhen Li
International Physical Medicine & Rehabilitation Journal, Volume 6, pp 11-14; doi:10.15406/ipmrj.2021.06.00271

Brigitte Nathalia Tascon Guevara
Pharmacy & Pharmacology International Journal, Volume 9, pp 7-9; doi:10.15406/ppij.2020.09.00318

Conrad Khisa Wanyama, George Wangila Butiki, John Wanjala Makokha, Fred Wekesa Masinde
International Journal of Hydrology, Volume 5, pp 23-26; doi:10.15406/ijh.2021.05.00261

This research measured the concentration levels of radon in groundwater and determined the ingestion and inhalation dose. The study used RAD7 detector with RAD7-H2O accessory from Durridge Company to determine the radon levels. Thirty water samples in granitic dominated regions were collected from various areas of Bungoma County: ten from boreholes (BH), ten from hand dug wells (WL) and ten from springs (SP). The water samples were collected in 250 ml bottles which were tightly covered with lid to avoid radon leakage. The highest value was 303±4.00 KBq/m3 recorded in Kanduyi well and the lowest was 126±11.4kBq/m3 from where most of the samples recorded a high radon concentration with a mean of 269±5.25 KBq/m3 in wells, 213±7.96 KBq/m3 in boreholes and 290±7.70 KBq/m3 in springs. The average ingestion dose was found to be 1.5±0.07mSv/yr, 1.9±0.09 mSv/yr and 2.1±0.1 mSv/yr. The average annual effective dose rate for the samples collected were 2±0.1 mSv/yr for boreholes, 2.6±0.13 mSv/yr for wells and 2.7±0.14 mSv/yr for springs. The samples reported an average value of AED higher than the world average of 1.15 mSv/yr but below the exception limit of recommended action level of 10 mSv/yr hence the radon concentration levels in underground water in the study area has minimal health implications to the population.
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