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(searched for: (10.5155/eurjchem.2.3.378-387.351))
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Sciprofile linkMohamed Abass, Elhossain Ali Mohamed, Mostafa Mohamed Ismail, Aisha Saleh Mayas
European Journal of Chemistry, Volume 2, pp 378-387; doi:10.5155/eurjchem.2.3.378-387.351

Abstract:
Preparation of quinolinyl-3-oxopropanoic acid was accomplished by hydrolysis of pyranoquinolinedione, in aqueous alkaline medium. The chemical behavior of this β-keto acid towards nitrosation, coupling with a diazonium salt, esterification, condensation with 2,2-diethoxyethanamine, hydrazinolysis, Knoevenagel condensation with isatine, salicylaldehyde, 3-formylquinolones, and 3-formylchromone, was investigated. Also many of the products of these reactions were obtained using either pyranoquinolinedione 1 or β-keto acid 2, under the same conditions.
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