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Sciprofile linkHae-Na Lee, Vikas Ashok, I. V. Ramakrishnan
HCI International 2020 – Late Breaking Papers: Universal Access and Inclusive Design pp 291-305; doi:10.1007/978-3-030-60149-2_23

Abstract:
Most computer applications manifest visually rich and dense graphical user interfaces (GUIs) that are primarily tailored for an easy-and-efficient sighted interaction using a combination of two default input modalities, namely the keyboard and the mouse/touchpad. However, blind screen-reader users predominantly rely only on keyboard, and therefore struggle to interact with these applications, since it is both arduous and tedious to perform the visual ‘point-and-click’ tasks such as accessing the various application commands/features using just keyboard shortcuts supported by screen readers. In this paper, we investigate the suitability of a ‘rotate-and-press’ input modality as an effective non-visual substitute for the visual mouse to easily interact with computer applications, with specific focus on word processing applications serving as the representative case study. In this regard, we designed and developed bTunes, an add-on for Microsoft Word that customizes an off-the-shelf Dial input device such that it serves as a surrogate mouse for blind screen-reader users to quickly access various application commands and features using a set of simple rotate and press gestures supported by the Dial. Therefore, with bTunes, blind users too can now enjoy the benefits of two input modalities, as their sighted counterparts. A user study with 15 blind participants revealed that bTunes significantly reduced both the time and number of user actions for doing representative tasks in a word processing application, by as much as \(65.1\%\) and \(36.09\%\) respectively. The participants also stated that they did not face any issues switching between keyboard and Dial, and furthermore gave a high usability rating (84.66 avg. SUS score) for bTunes.
Published: 25 September 2020
by MDPI
Sensors, Volume 20; doi:10.3390/s20195484

Abstract:
Scattering hyperspectral technology is a nondestructive testing method with many advantages. Here, we propose a method to improve the accuracy of egg freshness, research the influence of incident angles of light source on the accuracy, and explain its mechanism. A variety of weak classifiers classify eggs based on the spectra after preprocessing and feature wavelength extraction to obtain three classifiers with the highest accuracy. The three classifiers are used as metamodels of stacking ensemble learning to improve the highest accuracy from 96.25% to 100%. Moreover, the highest accuracy of scattering, reflection, transmission, and mixed hyperspectral of eggs are 100.00%, 88.75%, 95.00%, and 96.25%, respectively, indicating that the scattering hyperspectral for egg freshness detection is better than that of the others. In addition, the accuracy is inversely proportional to the angle of incidence, i.e., the smaller the incident angle, the camera collects a larger proportion of scattering light, which contains more biochemical parameters of an egg than that of reflection and transmission. These results are very important for improving the accuracy of non-destructive testing and for selecting the incident angle of a light source, and they have potential applications for online non-destructive testing.
Published: 25 September 2020
by MDPI
Brain Sciences, Volume 10; doi:10.3390/brainsci10100666

Abstract:
Background: Neuroinvasion of severe acute respiratory syndrome coronavirus (SARS-CoV) is well documented and, given the similarities between this virus and SARS-CoV-2, it seems that the neurological impairment that is associated with coronavirus disease 2019 (COVID-19) is due to SARS-CoV-2 neuroinvasion. Hypothalamic circuits are exposed to the entry of the virus via the olfactory bulb and interact centrally with crucial respiratory nuclei. Hypothalamic microRNAs are considered as potential biomarkers and modulators for various diseases and future therapeutic targets. The present study aims to investigate the microRNAs that regulate the expression of hypothalamic angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2), essential elements for SARS-CoV-2 cell entry. Methods: To determine potential hypothalamic miRNAs that can directly bind to ACE2 and TMPRSS2, multiple target bioinformatics prediction algorithms were used, including miRBase, Target scan, and miRWalk2.029. Results: Our in silico analysis has revealed that, although there are over 5000 hypothalamic miRNAs, around 31 miRNAs and 29 miRNAs have shown binding sites and strong binding capacity against ACE2 and TMPRSS2, respectively. Conclusion: These novel potential hypothalamic miRNAs can be used to identify new therapeutic targets to treat neurological symptoms in COVID-19 patients via regulation of ACE2 and TMPRSS2 expression.
Published: 25 September 2020
by MDPI
Applied Sciences, Volume 10; doi:10.3390/app10196697

Abstract:
In this research work, thermal foaming of bottom ash and sodium silicate geopolymer is proposed as a production process for light weight bricks. The composition and temperatures were studied and optimized to get the most suitable intumescence properties for the lightweight construction applications. For this purpose, four different compositions (i.e., 10%, 20%, 30%, and 40% bottom ash (BA)) were cured at four different curing temperatures (CT) (i.e., 200, 400, 500, and 600 °C). Sodium silicate (SS) to sodium hydroxide (SH) ratio was kept constant in order to keep the activation capacity of the solution constant in all the samples so that the effect of composition and CT could be studied effectively. All samples were characterized by bulk density, foamability, compression test, XRD, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), water absorption index (WAI), and weight loss index (WLI). These characterizations finally led to the optimized parameters to get the most appropriate intumescence properties. It was found that bottom ash and sodium silicate geopolymer foams have good potential to produce lightweight aerated blocks.
Frontier Information Technology and Systems Research in Cooperative Economics pp 847-855; doi:10.1007/978-3-030-57831-2_91

Abstract:
The paper analyzes financial conditions and development of the cooperative production sector of Russia. The empirical base is the financial statements of 1907 enterprises of the cooperative sector of Russia for 2014–2018. The methods of trend and correlation-regression analysis were used. A methodology for financial analysis and forecasting the development of the cooperative sector was developed and presented in the paper. The structure of the sector, cyclicality, and volatility of indicators are evaluated. The behavior of companies in the sector is analyzed in terms of operating, investment, and financial activities. The possibility of creating value by sector companies and the long-term growth rates of key indicators are analyzed. The methodology was tested on the data of sector enterprises. Indicators for the largest enterprises were separately calculated. The results show that the sector is non-cyclical, low concentrated. The most significant operators have a real economy of scale. The sector is heterogeneous, agricultural cooperatives dominate it. The operational efficiency of sector enterprises is declining, and investment and financial activity are low. The largest enterprises in the sector are characterized by higher operational efficiency and investment activity, they create value. Relying on the multivariate regression analysis, the author makes predictions regarding the financial results of enterprises in the sector, which are based on linear, logarithmic, and power-law trends. Also, the author forecasts operating expenses, identifying a moderate increase in revenue and a decrease in the profit of enterprises in the sector due to the pronounced positive economies of scale and increased intra-industry competition due to the monopolization of market infrastructure. The competitiveness of enterprises in the sector can be improved through government support for the formation of digital infrastructure.
Sciprofile linkIgor A. Vladimirov, Louise K. Rashitova, Radmir A. Iksanov
Frontier Information Technology and Systems Research in Cooperative Economics pp 777-785; doi:10.1007/978-3-030-57831-2_84

Abstract:
The paper reveals a comparative analysis of the legal status of personal subsidiary plots and peasant farms. The authors substantiate the idea of combining personal subsidiary farms of citizens in “social, agricultural cooperatives” on a territorial basis. Such an approach requires granting these cooperatives with the status of a subject of social entrepreneurship.
Anatoly E. Shamin, Tatiana N. Kutaeva, Sciprofile linkMarina L. Nechaeva, Vladimir A. Makarychev
Frontier Information Technology and Systems Research in Cooperative Economics pp 749-758; doi:10.1007/978-3-030-57831-2_81

Abstract:
Over the current year, the monitoring of economic development in the country made it possible to identify the increasing food production in the country, macroeconomic stabilization, and increased investment activity of organizations. Consumer cooperation is an important segment of the economy and has a diversified type of activity. Consumer cooperation makes a significant contribution to the budget development in rural settlements, and provides rural residents with basic necessities. The authors analyze the state of consumer cooperation organizations in Russia. The characteristics of consumer cooperation enterprises that potential buyers take into account when choosing are defined. These characteristics are the factors of enterprise competitiveness. Analysis of consumer preferences using factor analysis conducted; main directions of improving the activities of consumer cooperation enterprises identified. The research shows that for when potential buyers choose a consumer cooperative enterprise, the quality and range of goods and services become the decisive factors. A methodology for analyzing the influence of factors on the production of food products of consumer cooperation in the regional market is developed and presented in the paper. The proposed method is a tool that allows to improve the management process of consumer cooperation organizations, taking into account logically interconnected and settlement-based conclusions. Therefore, this method allows one to increase the efficiency of the organization and helps to improve competitive position in the market.
Elena A. Bryzgalova, Sciprofile linkMarina V. Kovshova, Olga V. Kolesnikova, Lidiya B. Larina, Olga I. Zhukova
Frontier Information Technology and Systems Research in Cooperative Economics pp 797-803; doi:10.1007/978-3-030-57831-2_86

Abstract:
The relevance of the study is due to the fact that global R&D spending in the pharmaceutical industry continues to grow every year, but the effectiveness of R&D is reduced. The pharmaceutical development process is the first and very important stage in the development of the new drug substance. The purpose of the study is to study the modern structure of the organization of pharmaceutical developments in large pharmaceutical companies. In the study, the authors used a systematic approach, inductive analysis, deductive analysis, content analysis method, comparison method. The study identified the main participants in the pharmaceutical development process in large pharmaceutical companies.
Sciprofile linkWiktor E. Panasenko, Mikhail A. Sharonov, Mikhail V. Boginya, Tatiana G. Vlasova, Zhanna S. Zhukova
Frontier Information Technology and Systems Research in Cooperative Economics pp 705-714; doi:10.1007/978-3-030-57831-2_76

Abstract:
There is a new understanding of the system and business strategy developing both in the industry and academia, the authors argue. Service is a system for ensuring a business’s stability and profitability, the formation of long-term competitive advantages, and company image, profit, and market share. The space-time system “service” is built from the model of the system of industrial segments, with the concept of the integral principle of constructing modules of segments and the “human”, as the key element. The critical module determines the direction of the industry. The system’s material and technical segment is the foundation on which the technical service system is based. This segment is not just an integral part of the automotive service system but also a critical element, forming the fundamental component of a service product. Companies operating in the segment develop the necessary foundation of the service business, contributing to its effective functioning and dynamic development. The authors describe a new format of relations that take on the character of partnership. The partnership goal is mutual benefit. The essence of the programs of the marked segment offered can be titled as “Program for the Formation, Support, and Development of the Client’s Business.” This program is based on a systematic approach to customer expectations, where the range of proposed solutions is a complete cycle. The program is a mechanism that allows one to learn to look more broadly at a business, understand its underlying patterns, and find optimal solutions. Considerable attention is paid to the technical support of customers through the Service and Training centers, as well as service support in management and marketing, financial and technical audits. As practice shows, in this area, substantial potential and reserves are hidden. Such growth would significantly contribute to a business’s successful operations and, accordingly, competitiveness.
Sciprofile linkVera V. Darinskaya, Oleg A. Antonyuk, Andrey A. Privetkin, Sciprofile linkLyudmila A. Kryatova, Elena V. Ivanova
Frontier Information Technology and Systems Research in Cooperative Economics pp 715-721; doi:10.1007/978-3-030-57831-2_77

Abstract:
The paper presents the results of a study on the implementation and use of strategic controlling, the stages of its formation, and their relationship with the areas of management development. The role of strategic controlling in a period of profound uncertainty of economic processes, in terms of forecasting and planning the financial result of activities. The research presented in the paper has highly important implications for cooperative enterprises working in Russia.
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