Antibacterial and Bonding Properties of Universal Adhesive Dental Polymers Doped with Pyrogallol
Open Access
- 11 May 2021
- Vol. 13 (10), 1538
- https://doi.org/10.3390/polym13101538
Abstract
This study investigated the antibacterial activity, bond strength to dentin (SBS), and ultra-morphology of the polymer–dentin interface of experimental adhesive systems doped with pyrogallol (PY), which is a ubiquitous phenolic moiety that is present in flavonoids and polyphenols. A universal adhesive containing 4-META and 10-MDP was used in this study. PY behaves as an antioxidant and anti-cancerogenic agent and it was incorporated into the adhesive at different concentrations (0.5 and 1 wt.%). The antibacterial activity and SBS were analyzed and the results were statistically analyzed. The ultra-morphology of the polymer–dentin interface was assessed using scanning electron microscopy (SEM). At 24 h, a lower antibacterial activity was observed for the control adhesive compared to those with 0.5% and 1% PY. No difference was seen in SBS between the three groups at 24 h. After 6 months, the SBS of the 0.5% PY adhesive was significantly lower than the other tested adhesives. The specimens created with 1% PY adhesive presented a higher bond strength at six months compared with that found at 24 h. No morphological differences were found at the polymer–dentin interfaces of the tested adhesives. Pyrogallol may be incorporated into modern universal adhesive systems to preserve the polymer–dentin bonding interface and confer a certain degree of antibacterial activity.This publication has 51 references indexed in Scilit:
- Dental primer and adhesive containing a new antibacterial quaternary ammonium monomer dimethylaminododecyl methacrylateJournal of Dentistry, 2013
- Optimizing dentin bond durability: Control of collagen degradation by matrix metalloproteinases and cysteine cathepsinsDental Materials, 2013
- Inhibitory effect onStreptococcus mutansand mechanical properties of the chitosan containing composite resinRestorative Dentistry & Endodontics, 2013
- Epigallocatechin-3-gallate (EGCG) enhances the therapeutic activity of a dental adhesiveJournal of Dentistry, 2012
- Therapeutic effect of glass-ionomers: an overview of evidenceAustralian Dental Journal, 2011
- The role of matrix metalloproteinases in the oral environmentActa Odontologica Scandinavica, 2007
- Iron-chelation properties of phenolic acids bearing catechol and galloyl groupsFood Chemistry, 2006
- Modeling and comparison of dissolution profilesEuropean Journal of Pharmaceutical Sciences, 2001
- Polyphenol interactions. Part 1. Introduction; some observations on the reversible complexation of polyphenols with proteins and polysaccharidesJournal of the Chemical Society, Perkin Transactions 2, 1985
- Clinical and Materials SciencesJournal of Dental Research, 1978