Crystal Type Iof Azilsartan Polymorphs: Preparation and Analysis
Open Access
- 1 January 2016
- journal article
- research article
- Published by Scientific Research Publishing, Inc. in Journal of Crystallization Process and Technology
- Vol. 06 (01), 1-10
- https://doi.org/10.4236/jcpt.2016.61001
Abstract
Azilsartan (2-ethoxy-1-([2’-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl)-1H-benzimidazole-7-carboxylic acid) is a new angiotensin II receptor antagonist used in the treatment of hypertension. This paper describes the preparation of type I crystal and its single crystal diffraction data, the comparison of the powder diffraction data for both type I and II crystals as well as their stability and solubility in methanol.Keywords
This publication has 3 references indexed in Scilit:
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- Enantiotropically Related Albendazole PolymorphsJournal of Pharmaceutical Sciences, 2010
- Supramolecular ChemistryPublished by Wiley ,2009