The term Feline Atopic Syndrome has been used to describe allergic food and/or environmental hypersensitivity, excluding all parasitic causes. The most evident clinical sign in this disease is intense itching, generating cervicofacial abrasions and symmetrical alopecia self-induced by trauma. As no clinical sign of this syndrome is pathognosomenic, diagnosis is difficult and involves the exclusion of all pruriginous dermatological causes. The treatment of this disease represents a challenge for veterinarians, since its physiopathogeny has not yet been well elucidated and has so far been considered incurable. This review will address the available treatments.