To review current information and technology for tooth remineralisation. Searches in the "Scopus" and "Web ofKnowledge" databases, which date back to 1970s. English was the only language allowed. The study incorporatedboth original research and previously published reviews. Tooth remineralisation agents, products, and treatmentshave progressively increased in recent years due to the growing awareness of the significance of good dentalhealth among patients and general community. Both in vitro and in vivo tooth remineralisation anddemineralization research have been published regularly. Theobromine has been proposed as an effectiveremineralising agent and a viable alternative to fluorides in recent years. According to research, fluoride treatmentscan prevent dental enamel demineralization and remineralisation. An increasing number of products containingcalcium salts or calcium-based compounds have been added to oral care products to boost the delivery andretentiveness of fluoride into teeth. Calcium salts or materials, which provide an additional source of calcium,may aid in accelerating enamel remineralisation or hinder demineralization processes. These effects are possiblebecause calcium is a mineral. A new area of research inspired by bioactive materials for bone repair andregeneration, bioglass, in particular calcium silicates, shows promise for improving enamel health and is one typeof bioglass that contains calcium silicate.