Ni-Catalyzed asymmetric hetero-Diels–Alder reactions of conjugated vinyl azides: synthesis of chiral azido polycycles
- 8 February 2021
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic Chemistry Frontiers
- Vol. 8 (8), 1770-1774
- https://doi.org/10.1039/d0qo01597k
Abstract
We report herein an efficient Ni(ii)/Feng ligand-catalyzed asymmetric hetero-Diels–Alder reaction between conjugated vinyl azides with carbonyl groups, providing a synthesis of complicated chiral azido polycycles in high yields and excellent enantioselectivities.Keywords
Funding Information
- National Natural Science Foundation of China (21971149, ZR2018MB010, ZR2019ZD45, ZR2019BB060)
- Natural Science Foundation of Shandong Province (21971149, ZR2018MB010, ZR2019ZD45, ZR2019BB060)
- Fundamental Research Fund of Shandong University
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