The Influence of Laparoscopic Sleeve Gastrectomy on Body Composition and Fat Distribution in Obese Caucasian Men and Women

Abstract

Background The aim of the study was to assess changes in body composition in patients subjected to laparoscopic sleeve gastrectomy (LSG). Methods Changes in body composition following LSG were determined in a group of 155 patients with obesity (117 women and 38 men), with dual-energy X-ray absorptiometry (DXA). Whole body fat mass (FM) and lean body mass (LBM) were determined, and abdominal fat mass (AbdF) was assessed within the region extending from the top of the pubic bone up to the line between 12th thoracic and 1st lumbar vertebras. Results Over the period of 12 months following LSG, body mass index decreased by 28.2 +/- 9.0% (p < 0.001). The reduction of body weight by 35.4 +/- 12.6 kg (p < 0.001) was the result of a decrease in FM by 23.9 +/- 8.9 kg (p < 0.001) and LBM by 10.5 +/- 3.8 kg (p < 0.001). AbdF decreased from 13.2 +/- 3.1 to 8.2 +/- 2.7 kg (p < 0.001), but abdominal fat to total fat mass ratio increased from 24.9 +/- 4.7 to 28.0 +/- 5.8% (p < 0.001). The loss of AbdF was more pronounced in men than in women. The rate of FM loss was attenuated with patients' age. Conclusions Over the period of 12 months following LSG, the reduction of FM was more than twice as much as decrease of LBM. The loss of AbdF was slower than a loss of peripheral subcutaneous fat.