Abstract
Congenital absence of the left circumflex artery is a very rare congenital anomaly of the coronary arteries. Few cases have been reported in the literature. It is often an incidental finding following the request for cardiac imaging investigations due to the presence of chest pain of uncertain nature associated with a doubtful or positive stress test for suspected inducible ischemia. Consequently, computed tomography coronary angiography is the ideal diagnostic tool that is often used nowadays to confirm this suspicion and thus reliably diagnose this unique morphology. In this report the author describes the clinical case of a middle-aged patient with chest discomfort during effort followed by a positive cycle-ergometer Ex_ECG stress test for inducible myocardial ischemia.