Microstructure, biodegradable behavior in different simulated body fluids, antibacterial effect on different bacteria and cytotoxicity of rolled Zn–Li–Ag alloy

Abstract
Rolled Zn-0.8Li-0.2Ag(wt%) alloy as candidates for biodegradable materials. The biodegradable behavior of Zn-0.8Li-0.2Ag alloy in different solutions (Ringer's, DMEM, SBF and DMEMp) was investigated. The cytotoxicity of Zn-0.8Li-0.2Ag alloy and its antibacterial properties against staphylococcus aureus, enterobacter faecalis and candida albicans were evaluated. The results showed that Zn-0.8Li-0.2Ag alloy consists of zinc matrix and a LiZn4 secondary phase. The presence of Cl causes locally corroded of Zn-0.8Li-0.2Ag alloy in Ringer's solution, and its corrosion resistance is lower than that of the alloy which is uniformly corroded in other solutions containing CO3 2− and PO4 3−. Zn-0.8Li-0.2Ag alloy is non-toxic and exhibits better antibacterial properties than the experimental reference group without silver.
Funding Information
  • Natural Science Foundation of Hunan Province (2018JJ2506)
  • Natural Science Foundation of Shandong Province (ZR2017MEM005)

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