Abstract
COronaVIrus Disease‐19 (COVID‐19) is an infection due to a virus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2). This virus was first identified in Wuhan (China) in December 2019 and, subsequently, it has rapidly spread throughout the world. Although the most common symptoms of COVID‐19 are fever, cough, shortness of breath, headache and muscle pain, skin manifestations (symptoms) associated with this disease have been reported more and more frequently in recent times. In this review article, we have gathered clinical data on COVID‐19‐associated skin manifestations by analysing the articles published up to the 30th of April 2020 and available on the electronic databases PubMed, Scopus and Web of Science. Based on the clinical appearance of the skin manifestations, six main patterns have been recognized: i) urticarial rash, ii) confluent erythematous/maculopapular/morbilliform rash, iii) papulovesicular exanthem, iv) chilblain‐like acral pattern, v) livedo reticularis/racemosa‐like pattern, and vi) purpuric “vasculitic” pattern. The clinical (how they look) and histopathological (from skin samples) features of these manifestations are discussed in detail in the manuscript. In view of the low number of experimental studies on this absolutely new topic, the exact mechanisms explaining the occurrence of such different skin lesions in COVID‐19 patients need to be further explored. Likewise, the possible correlation between skin manifestations and disease severity will be the subject of future studies. However, at the present time, clinicians, and particularly dermatologists, should be aware that the presence of certain cutaneous (skin) findings could indicate COVID‐19 and help to identify potentially contagious cases. Linked Article: Marzano et al. Br J Dermatol 2020; 183:431–442.