The herbal medicines are used in the ailment of several diseases from the ancient time. India is known worldwide for its Ayurvedic treatment. Scindapsus officinalis is often used traditionally for erectile disorders, respiratory diseases such as cough, bronchitis, pharyngitis, asthma and other worm infestation, dysentery, troubles of the throat, ozoena, rheumatism arthritis, and diarrhea. It is also used as carminative, anthelmintic, cardiotonic, diaphoretic, antiprotozoal (fruit), hypoglycemic (stem and fruit), anti-inflammatory, analgesic, antiasthmatic, cytostatic and antimicrobial steroids, flavonoids, and terpenoid which are characterized in the ethanolic extract of S. officinalis. This review describes the general information (distribution and plant description), description (macroscopic and microscopic), chemistry, ethnopharmacology, traditional uses, medicinal uses, and other important information about the plant S. officinalis.