Assessment of the inhibition risk of paris saponins, bioactive compounds from Paris polyphylla, on CYP and UGT enzymes via cocktail inhibition assays
- 1 June 2020
- journal article
- research article
- Published by Elsevier BV in Regulatory Toxicology and Pharmacology
- Vol. 113, 104637
- https://doi.org/10.1016/j.yrtph.2020.104637
Abstract
No abstract availableFunding Information
- National Natural Science Foundation of China (81773808, 81872418)
- Science and Technology Commission of Shanghai Municipality (18ZR1431700, 18430760400)
- Medical and Health Sciences in Shangha (2017YQ048)
- ECNU (011)
- National Natural Science Foundation of China (81773808, 81872418)
- Science and Technology Commission of Shanghai Municipality (18ZR1431700, 18430760400)
- Medical and Health Sciences in Shanghai (2017YQ048)
This publication has 36 references indexed in Scilit:
- Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approachToxicology Letters, 2019
- Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-κB pathwayPharmacological Research, 2018
- Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomesToxicology Letters, 2018
- The impact of CYP2D6 mediated drug–drug interaction: a systematic review on a combination of metoprolol and paroxetine/fluoxetineBritish Journal of Clinical Pharmacology, 2018
- Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1Acta Pharmaceutica Sinica. B, 2017
- Drug Metabolism in the LiverClinics in Liver Disease, 2016
- Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approachScientific Reports, 2016
- Phenobarbital Induction and Chemical Synergism Demonstrate the Role of UDP-Glucuronosyltransferases in Detoxification of Naphthalophos by Haemonchus contortus LarvaeAntimicrobial Agents and Chemotherapy, 2014
- Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblastsCell Communication and Signaling, 2012
- Clinical consequences of cytochrome P450 2C9 polymorphismsClinical Pharmacology & Therapeutics, 2005