Guidelines for the medical management of pediatric vesicoureteral reflux
Open Access
- 1 June 2020
- journal article
- research article
- Published by Wiley in International Journal of Urology
- Vol. 27 (6), 480-490
- https://doi.org/10.1111/iju.14223
Abstract
Urinary tract infection is a bacterial infection that commonly occurs in children. Vesicoureteral reflux is a major underlying precursor condition of urinary tract infection, and an important disorder in the field of pediatric urology. Vesicoureteral reflux is sometimes diagnosed postnatally in infants with fetal hydronephrosis diagnosed antenatally. Opinions vary regarding the diagnosis and treatment of vesicoureteral reflux, and diagnostic procedures remain debatable. In terms of medical interventions, options include either follow-up observation in the hope of possible spontaneous resolution of vesicoureteral reflux with growth/development or provision of continuous antibiotic prophylaxis based on patient characteristics (age, presence/absence of febrile urinary tract infection, lower urinary tract dysfunction and constipation). Furthermore, there are various surgical procedures with different indications and rationales. These guidelines, formulated and issued by the Japanese Society of Pediatric Urology to assist medical management of pediatric vesicoureteral reflux, cover the following: epidemiology, clinical practice algorithm for vesicoureteral reflux, syndromes (dysuria with vesicoureteral reflux, and bladder and rectal dysfunction with vesicoureteral reflux), diagnosis, treatment (medical and surgical), secondary vesicoureteral reflux, long-term prognosis and reflux nephropathy. They also provide the definition of bladder and bowel dysfunction, previously unavailable despite their close association with vesicoureteral reflux, and show the usefulness of diagnostic tests, continuous antibiotic prophylaxis and surgical intervention using site markings.This publication has 105 references indexed in Scilit:
- Prevalence and Predictors of Renal Functional Abnormalities of High Grade Vesicoureteral RefluxJournal of Urology, 2013
- Observation of Patients with Vesicoureteral Reflux Off Antibiotic Prophylaxis: Physician Bias on Patient Selection and Risk Factors for Recurrent Febrile Urinary Tract InfectionJournal of Urology, 2012
- Current management of antenatal hydronephrosisPediatric Nephrology, 2012
- Transvesicoscopic cross-trigonal ureteroneocystostomy in children: A single-center experienceJournal of Pediatric Urology, 2012
- Antenatal and postnatal ultrasound in the evaluation of the risk of vesicoureteral refluxPediatric Nephrology, 2010
- Imaging studies for first urinary tract infection in infants less than 6 months old: can they be more selective?Pediatric Nephrology, 2009
- Is continuous antibiotic prophylaxis in children with vesicoureteral reflux really ineffective in preventing pyelonephritis?Pediatric Nephrology, 2009
- Endoscopic Treatment of Vesicoureteral Reflux with Dextranomer/Hyaluronic Acid in ChildrenAdvances in Urology, 2008
- Endoscopic Cross-Trigonal Ureteral Reimplantation Under Carbon Dioxide Bladder Insufflation: A Novel TechniqueJournal of Endourology, 2005
- Tubular proteinuria in reflux nephropathy: post ureteric re-implantationPediatric Nephrology, 1996