Peripheral dentinogenic ghost cell tumor—report of two cases and review of the literature
- 14 February 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Oral and Maxillofacial Surgery
- Vol. 25 (4), 575-579
- https://doi.org/10.1007/s10006-021-00947-x
Abstract
Peripheral dentinogenic ghost cell tumor (DGCT) is a rare and non-aggressive benign odontogenic tumor. They usually affect the elderly and are predominantly located in the anterior region of the jaws. Their differential diagnosis includes reactive/inflammatory gingival lesions. We report here two cases of peripheral DGCT in a 73-year-old female and a 48-year-old male patient and review the cases published in the literature. Both lesions presented as a nodular lesion in the mandible, and panoramic radiography showed no abnormalities. Microscopically, it was observed to be an ameloblastomatous epithelial proliferation associated with clusters of ghost cells and dysplastic dentin. Immunohistochemistry revealed positivity for cytokeratin 19 and a low Ki-67 proliferative index. Based on histopathological features and the absence of radiographic findings, a diagnosis of peripheral DGCT was rendered. The low number of cases published of peripheral DGCT makes case reports important in providing information that helps in their diagnoses and management.Keywords
This publication has 23 references indexed in Scilit:
- A glance to 2011Dental Research Journal, 2012
- Dentinogenic Ghost Cell Tumor of the Peripheral Variant Mimicking EpulisInternational Journal of Dentistry, 2010
- Peripheral dentinogenic ghost cell tumor: a case report and review of the literatureOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2009
- Peripheral dentinogenic ghost cell tumour in child: A case reportInternational Journal of Pediatric Otorhinolaryngology Extra, 2007
- Peripheral Dentinogenic Ghost Cell Tumor of the GingivaThe Journal of Periodontology, 2007
- Peripheral dentinogenic ghost cell tumour presenting as a gingival massBritish Journal of Oral and Maxillofacial Surgery, 2004
- Peripheral dentinogenic ghost cell tumorJournal of Oral Pathology & Medicine, 1992
- Dentinogenic ghost cell tumorInternational Journal of Oral & Maxillofacial Surgery, 1987
- Calcifying Odontogenic CystActa Odontologica Scandinavica, 1981
- The calcifying odontogenic cyst: Report of four casesOral Surgery, Oral Medicine, Oral Pathology, 1968