COVID-19—White matter and globus pallidum lesions
Open Access
- 1 July 2020
- journal article
- editorial
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology Neuroimmunology & Neuroinflammation
Abstract
Since December 2019, a novel coronavirus, also called severe acute respiratory syndrome CoV-2 (SARS-CoV-2), emerged in Wuhan, China, and caused a pandemic disease (COVID-19). Respiratory impairment is the most common symptom in patients with confirmed COVID-19; however, neurologic symptoms were documented in approximately 36%, including headache, disturbed consciousness, and paresthesia.(1)The virus can take different pathways to involve the CNS: in one way through hematogenous or lymphatic route and in another way via the cribriform plate close to the olfactory bulb. Very few studies have shown CNS abnormalities related to COVID-19 on MRI. Herein, we report a case of SARS-CoV-2 brain lesions suggesting an acute demyelination.Keywords
This publication has 8 references indexed in Scilit:
- COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: Imaging FeaturesRadiology, 2020
- Neurologic Features in Severe SARS-CoV-2 InfectionThe New England Journal of Medicine, 2020
- Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, ChinaJAMA Neurology, 2020
- Nervous system involvement after infection with COVID-19 and other coronavirusesBrain, Behavior, and Immunity, 2020
- Detection of Coronavirus in the Central Nervous System of a Child With Acute Disseminated EncephalomyelitisPEDIATRICS, 2004
- Macrophage Infiltration, but Not Apoptosis, Is Correlated with Immune-Mediated Demyelination following Murine Infection with a Neurotropic CoronavirusJournal of Virology, 1999