Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease Virus
Open Access
- 4 September 2020
- Vol. 9 (9), 729
- https://doi.org/10.3390/pathogens9090729
Abstract
Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in cloven-hoofed livestock that results in severe consequences for international trade, posing a great economic threat to agriculture. The FMDV infection antagonizes the host immune responses via different signaling pathways to achieve immune escape. Strategies to escape the cell immune system are key to effective infection and pathogenesis. This review is focused on summarizing the recent advances to understand how the proteins encoded by FMDV antagonize the host innate and adaptive immune responses.This publication has 151 references indexed in Scilit:
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