Background: This study aimed to determine the prevalence of Diabetic Retinopathy and to find the associated risk factors of DR among known Type II DM patients. Materials and Methods: A hospital-based cross-sectional and single center study was conducted among Type II DM patients with and without DR in the department of Endocrinology with a sample size of 150 with DM patients in 2018. Data were expressed as mean, standard deviation, proportions, Chi-Square, t-test test and Binary Logistic Regression analysis. Results: Diabetic patients 150 were identified as Type II DM as per inclusion criteria with aged 30 years and above. Among 150 Diabetic patients, 39 (26%) patients had Diabetic Retinopathy and 111 (74%) patients were not having Diabetic Retinopathy. The association between groups (with and no DR) and duration of DM were very highly significant with p-value < 0.01. DR prevalence was higher in female when compared with male population. Conclusion: From our study, we have concluded that the prevalence of DR was very high. DR was strongly associated with HbA1C, FBS, duration of DM, medication, duration of hypertension and smoking. Hence, there is a need for regular screening check-up with ophthalmologist to prevent diabetic retinopathy or to prolong or to escape from the vision loss. Keywords: type II diabetic mellitus, diabetic retinopathy, prevalence, risk factors