Development and validation of a liquid chromatographic method for the determination of nitrofuran residues in fish samples
- 18 May 2022
- journal article
- Published by Association For Science (Publications)
- Vol. 55, 60-63
- https://doi.org/10.52340/csw.2022.05.927
Abstract
A sensitive, accurate and efficient liquid chromatographic method has been developed for determination of nitrofuran residues in a honey sample; It was found that the detection minimum for all four nitrofuran group substances is 0.03 μg / ml, the specific wavelength is 376 nm, the specificity coefficient of variation for both on one working day and one working week is 0.99); Sample preparation is satisfactory as the obtained sampling coefficient is> 0.6. Thus, as a result of validation of the liquid chromatographic method developed for the quantitative determination of nitrofuran residues in the honey sample, the method was fully complied with the requirements of the Government of Georgia according to the following validation characteristics: detection minimum, specificity, accuracy, correctness and linearity. (#499, Guidance for Industry Bioanalytical Method Validation U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Veterinary Medicine (CVM) May 2001).Keywords
This publication has 4 references indexed in Scilit:
- Adapting national legislation to Directive 2017/164/EU and to Directive 2017/2398/EU amending Directive 2004/37/ECPrinciples and Methods of Assessing the Walking Environment, 2018
- About CC? and CC? as introduced by the Commission Decision of 12 August 2002 implementing Council Directive 96/23/ECAccreditation and Quality Assurance, 2004
- Commission decision of 29 Nov 2002 establishing revised ecological criteria for the award of the Community eco-label to detergents for dishwashers and amending Decision 1999/427/ECFocus on Surfactants, 2003
- Reviewer Guidance: Review of Human Pregnancy Outcome DataPublished by Test accounts ,1999