Prevalence of mammary Paget’s disease in urban China in 2016
Open Access
- 28 January 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in Scientific Reports
- Vol. 11 (1), 1-8
- https://doi.org/10.1038/s41598-021-82146-y
Abstract
No national data have been available on descriptive epidemiology of mammary Paget’s disease (MPD) in China. This population-based study aimed to estimate the prevalence of MPD and its pattens by sex, age and area in China. We conducted a population-based study using data in 2016 from China’s Urban Employee Basic Medical Insurance and Urban Resident Basic Medical Insurance, covering approximately 0.43 billion residents. MPD cases were identified based on the diagnostic names and codes in claim data. A total of 825 patients of confirmed diagnosis of MPD were found during the study period. The prevalence of MPD in 2016 was 0.42 per 100,000 population (95% CI 0.19 to 0.73), with marked female predominance. The prevalence rates peaked at 40–59 years and ≥ 80 years in females and males, respectively. The prevalence rates varied among different regions, ranging from 0.06 (95% CI 0.00 to 0.23) in Northeast China to 1.21 (95% CI 0.07 to 3.72) in Northwest China. MPD showed marked female predominance in China. Chinese female patients were much younger, with lower prevalence than that in the United States. Obvious sex difference in the age pattern of MPD prevalence was also observed in China.Funding Information
- National Natural Science Foundation of China (91646107, 81973146)
This publication has 65 references indexed in Scilit:
- Prevalence ofBRCA1andBRCA2Germline Mutations in Breast Cancer Women of Multiple Ethnic Region in Northwest ChinaJournal of Breast Cancer, 2013
- Improving Breast Cancer Outcomes among Women in China: Practices, Knowledge, and Attitudes Related to Breast Cancer ScreeningInternational Journal of Breast Cancer, 2012
- Paget′s disease of the breastJournal of Carcinogenesis, 2011
- Expression of cell cycle proteins in male breast carcinomaWorld Journal of Surgical Oncology, 2010
- Gynaecomastia and breast cancer in menBMJ, 2008
- Paget’s disease of the breast: the experience of the European institute of oncology and review of the literatureBreast Cancer Research and Treatment, 2008
- Clinicopathologic evaluation of mammary Paget's diseaseIndian Journal of Dermatology, 2008
- Paget’s disease of the nipple in a population based cohortBreast Cancer Research and Treatment, 2007
- Mammary and extramammary Paget's diseaseJournal of the European Academy of Dermatology and Venereology, 2007
- Challenges of Using Medical Insurance Claims Data for Utilization AnalysisAmerican Journal of Medical Quality, 2006