Modern possibilities of infusion therapy in patients with diabetic ketoacidosis
Open Access
- 10 October 2020
- journal article
- Published by Communicable Diseases Intensive Care Association in Infusion & Chemotherapy
- No. 3,p. 11-17
- https://doi.org/10.32902/2663-0338-2020-3-11-17
Abstract
The mechanisms of development and clinical manifestations of diabetic ketoacidosis (DKA) are analyzed in the article, the prospects of the use of xylitol-based infusions in the treatment of DKA are discussed. The authors also presented the infusion therapy program and their own experience with the use of Xylat solution. It has been shown that the use of Xylat can have a positive effect on various parts of the pathological process – from elimination of dehydration to the correction of disorders of acid-base status (ABS). Xylat should be started with the first signs of DKA, even in the absence or low severity of ketonuria according to the nitroprusside test. This tactic makes it possible to normalize ABS more quickly and reduce the overall amount of infusion therapy.Keywords
This publication has 7 references indexed in Scilit:
- Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patientsBMJ, 2019
- 15. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2019Diabetes Care, 2018
- The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and managementMetabolism, 2015
- Electrolyte and Acid–Base Disturbances in Patients with Diabetes MellitusThe New England Journal of Medicine, 2015
- Bicarbonate in diabetic ketoacidosis - a systematic reviewAnnals of Intensive Care, 2011
- Hyperglycemic Crises in Adult Patients With DiabetesDiabetes Care, 2009
- Hyperglycaemic crises and lactic acidosis in diabetes mellitusPublished by Oxford University Press (OUP) ,2004