A ratiometric fluorescent probe for monitoring pH fluctuations during autophagy in living cells
- 4 January 2021
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 57 (12), 1510-1513
- https://doi.org/10.1039/d0cc07788g
Abstract
We present a ratiometric fluorescent probe for monitoring pH featuring superb photostability and chemostability. The down-regulation of the intracellular pH during autophagy in living cells induced by various stimuli, including several drugs and starvation, was quantified, which could provide instructive value to construct autophagy models to study the related pathological processes.Keywords
Funding Information
- National Natural Science Foundation of China (21807029)
- Foundation of Henan Educational Committee (20A150036)
- Hubei Provincial Department of Education (Q20182704)
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