Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease
Open Access
- 16 July 2020
- journal article
- research article
- Published by S. Karger AG in Case Reports in Oncology
- Vol. 13 (2), 853-856
- https://doi.org/10.1159/000508531
Abstract
Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age.Keywords
This publication has 7 references indexed in Scilit:
- Unicentric Castleman DiseaseHematology/Oncology Clinics of North America, 2018
- Epidemiology of Castleman DiseaseHematology/Oncology Clinics of North America, 2018
- Surgery in Castleman's DiseaseAnnals of Surgery, 2012
- Castleman DiseaseAdvances in Anatomic Pathology, 2009
- Surgical management of abdominal and retroperitoneal Castleman's diseaseWorld Journal of Surgical Oncology, 2005
- Castleman Disease of the Abdomen: Imaging Spectrum and Clinicopathologic CorrelationsJournal of Computer Assisted Tomography, 2001
- Hyaline‐vascular and plasma‐cell types of giant lymph node hyperplasia of the mediastinum and other locationsCancer, 1972