Brain-computer interface's (BCI) potential applications increased tremendously over the past decade. The rising of this new technology is providing promising solutions in the field of aerospace and space exploration. As astronauts face diverse challenges in long-duration spaceflight, BCI can help astronauts deal with complicated tasks with a minimal mental workload. It may provide intelligent communication systems, maximize safety and security, facilitate space discovery missions, and enhance astronauts' overall health and wellbeing. In new ventures such as SpaceX, Starlink, and Neuralink, pioneers adopt futuristic strategies that use BCI as their main anchor. Such efforts are valuable in neuroscience as they will reveal information that will allow neuroscientists to deeper understand the brain's mechanisms.