Haematuria either gross or microscopic has always worried the urologist as it raises the suspicion of malignancy in the genito-urinary tract (GUT). Benign causes of haematuria include inflammation, calculus, infection and trauma to the GUT. Amyloidosis is a very rare but benign cause of haematuria. The important issue is that it simulates transitional cell carcinoma of urinary bladder in presentation, imaging, endoscopic and gross appearance. However the treatment plan and prognosis of both condition is different ranges from various bladder preservation methods to radical cystectomy. Thus an amyloidosis is an important differential of carcinoma urinary bladder that to be should be consider in patients with bladder mass.