The Ubiquitin Switch in Plant Stress Response
Open Access
- 27 January 2021
- Vol. 10 (2), 246
- https://doi.org/10.3390/plants10020246
Abstract
Ubiquitin is a 76 amino acid polypeptide common to all eukaryotic organisms. It functions as a post-translationally modifying mark covalently linked to a large cohort of yet poorly defined protein substrates. The resulting ubiquitylated proteins can rapidly change their activities, cellular localization, or turnover through the 26S proteasome if they are no longer needed or are abnormal. Such a selective modification is essential to many signal transduction pathways particularly in those related to stress responses by rapidly enhancing or quenching output. Hence, this modification system, the so-called ubiquitin-26S proteasome system (UPS), has caught the attention in the plant research community over the last two decades for its roles in plant abiotic and biotic stress responses. Through direct or indirect mediation of plant hormones, the UPS selectively degrades key components in stress signaling to either negatively or positively regulate plant response to a given stimulus. As a result, a tightly regulated signaling network has become of much interest over the years. The ever-increasing changes of the global climate require both the development of new crops to cope with rapid changing environment and new knowledge to survey the dynamics of ecosystem. This review examines how the ubiquitin can switch and tune plant stress response and poses potential avenues to further explore this system.Keywords
Funding Information
- National Science Foundation (MCB-1750361)
This publication has 166 references indexed in Scilit:
- The Arabidopsis NPR1 Protein Is a Receptor for the Plant Defense Hormone Salicylic AcidCell Reports, 2012
- NPR3 and NPR4 are receptors for the immune signal salicylic acid in plantsNature, 2012
- The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognitionNature Reviews Molecular Cell Biology, 2010
- Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptorNature, 2010
- Arabidopsis resistance protein SNC1 activates immune responses through association with a transcriptional corepressorProceedings of the National Academy of Sciences of the United States of America, 2010
- Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expressionProceedings of the National Academy of Sciences of the United States of America, 2006
- The plant immune systemNature, 2006
- Structural Basis for E2-Mediated SUMO Conjugation Revealed by a Complex between Ubiquitin-Conjugating Enzyme Ubc9 and RanGAP1Cell, 2002
- Plant pathogens and integrated defence responses to infectionNature, 2001
- The Arabidopsis NPR1 Gene That Controls Systemic Acquired Resistance Encodes a Novel Protein Containing Ankyrin RepeatsCell, 1997