Study of Curcumin Adsorption of Nano Fe-based Metal-Organic Framework

Abstract

Highly porous and biocompatible nano metal-organic framework materials (NMOF) are increasingly being applied in biomedical fields, especially as pharmaceutical adsorbent materials. Curcumin, found in turmeric, is a widely common herb in Eastern which has recently used in many applications in supporting cancer treatment. In the synthesis of MOF materials, the use of surfactants allows to control the morphology, the process of crystal formation and development and particle size of the material. In this research, MIL-100 (Fe) nanomaterials were successfully synthesized at room temperature in the presence of polyvinylpyrrolidone surfactant (PVP) to control the nanoparticle size about 50 nm in size. The synthesized MOF structure and properties were analyzed by using characterization techniques, including powder X-ray diffraction (PXRD), fourier-transform infrared (FT-IR), thermal gravimetric analyses (TGA) and nitrogen isothermal adsorption-desorption at 77 K. The characterization results showed that MIL-100 (Fe) nanomaterials have high crystallinity, large surface area, and highly thermal stability. However, its particle size is very small, only about 50 nm. Curcumin adsorption studies exhibited that this material had the ability to adsorb curcumin with an adsorption capacity up to 64.36 mg g-1. Kinetic and mechanism studies revealed that curcumin adsorption followed the pseudo-second model. In addition, thermodynamic studies proved that this was a spontaneous and exothermic adsorption process.