Acute BAF perturbation causes immediate changes in chromatin accessibility

Abstract

Cancer-associated, loss-of-function mutations in genes encoding subunits of the BRG1/BRM-associated factor (BAF) chromatin-remodeling complexes^{1,2,3,4,5,6,7,8} often cause drastic chromatin accessibility changes, especially in important regulatory regions^{9,10,11,12,13,14,15,16,17,<a data-track="click" data-track-action="reference anchor"...}