Bioluminescence-Driven Optogenetics
Open Access
- 28 November 2020
- Vol. 10 (12), 318
- https://doi.org/10.3390/life10120318
Abstract
Bioluminescence-based technologies are among the most commonly used methods to quantify and visualise physiology at the cellular and organismal levels. However, the potential of bioluminescence beyond reporter technologies remains largely unexplored. Here, we provide an overview of the emerging approaches employing bioluminescence as a biological light source that triggers physiological events and controls cell behaviour and discuss its possible future application in synthetic biology.Keywords
This publication has 80 references indexed in Scilit:
- AAV-Mediated, Optogenetic Ablation of Müller Glia Leads to Structural and Functional Changes in the Mouse RetinaPLOS ONE, 2013
- Light Scattering Properties Vary across Different Regions of the Adult Mouse BrainPLOS ONE, 2013
- Light-Emitting Channelrhodopsins for Combined Optogenetic and Chemical-Genetic Control of NeuronsPLOS ONE, 2013
- Novel multistep BRET-FRET energy transfer using nanoconjugates of firefly proteins, quantum dots, and red fluorescent proteinsNanoscale, 2013
- The Development and Application of OptogeneticsAnnual Review of Neuroscience, 2011
- Optogenetics in Neural SystemsNeuron, 2011
- Filtering of Visual Information in the Tectum by an Identified Neural CircuitScience, 2010
- Photophysics and photochemistry of photodynamic therapy: fundamental aspectsLasers in Medical Science, 2008
- A genetically encoded photosensitizerNature Biotechnology, 2005
- Toxicity of the bacterial luciferase substrate, n‐decyl aldehyde, to Saccharomyces cerevisiae and Caenorhabditis elegansFEBS Letters, 2001