Reexamining the Association of AmpC Variants with Enterobacter Species in the Context of Updated Taxonomy

Abstract

We performed whole-genome sequencing for 17 Enterobacter clinical strains and analyzed all available Enterobacter genomes and those of its closely related genera ( n = 3,389) from NCBI. The exact origins of plasmid-borne bla _CMH and bla _MIR genes are Enterobacter cloacae and Enterobacter roggenkampii , respectively, while plasmid-borne bla _ACT genes originated from multiple other Enterobacter species, including Enterobacter xiangfangensis , Enterobacter hoffmannii , Enterobacter asburiae , Enterobacter ludwigii , and Enterobacter kobei .