Multiple Metastases of Observed Osteosarcoma Case in A Belgian Malinois Race Female Dog
- 22 November 2019
- journal article
- Published by Van Veterinary Journal in Van Veterinary Journal
- Vol. 30 (3), 197-200
- https://doi.org/10.36483/vanvetj.551217
Abstract
In this study, we aimed to evaluate histopathologically the case of osteosarcoma detected in an Belgian Malinois race dog. The material of the study consisted of a 8.5-year-old Belgian Malinois race female dog weighing 30 kg. With the complaints of abdominal distention, difficulty in breathing, loss of appetite, fatigue, the dog brought to the Veterinary Faculty of Kafkas University Animal Hospital died on the way and was sent to the Department of Pathology for necropsy. In the follow-up, some of the tissue samples taken from the systemic necropsy animal were determined in the decalcified solution and another part in the buffered formaldehyde solution. Following routine procedures, 5 μm thick sections were taken from the prepared paraffin blocks for Hematoxylin Eosin staining. To determine the histopathological changes, the sections were examined by light microscope. In the light of the histopathological findings, osteosarcoma was diagnosed in the brain and lung metastatic foci.Keywords
This publication has 29 references indexed in Scilit:
- Wnt/β-Catenin Expression Does Not Correlate with Serum Alkaline Phosphatase Concentration in Canine Osteosarcoma PatientsPLOS ONE, 2011
- Expression of Hepatocyte Growth Factor and the Proto-oncogenic Receptor c-Met in Canine OsteosarcomaVeterinary Pathology, 2009
- Expression of Connexins in Normal and Neoplastic Canine Bone TissueVeterinary Pathology, 2009
- Investigating TrkA Expression in Canine Appendicular OsteosarcomaJournal of Veterinary Internal Medicine, 2008
- Glucose transporter 1 expression in canine osteosarcomaVeterinary and Comparative Oncology, 2008
- Characterization of the biological behaviour of appendicular osteosarcoma in Rottweilers and a comparison with other breeds: a review of 258 dogs*Veterinary and Comparative Oncology, 2007
- Antineoplastic effect of the cyclooxygenase inhibitor meloxicam on canine osteosarcoma cellsResearch in Veterinary Science, 2006
- Cyclooxygenase‐2 Expression in Canine Appendicular OsteosarcomasJournal of Veterinary Internal Medicine, 2004
- Multipotential Osteosarcoma with Various Mesenchymal Differentiations in a Young DogVeterinary Pathology, 2004
- A Study of the Lifetime Occurrence of Neoplasia and Breed Differences in a Cohort of German Shepherd Dogs and Belgian Malinois Military Working Dogs that Died in 1992Journal of Veterinary Internal Medicine, 2000