Atherogenic indices in clinical practice and biomedical research: A short review
Open Access
- 1 April 2021
- journal article
- Published by Department of Chemistry and Biochemistry, Al-Nahrain University in Baghdad Journal of Biochemistry and Applied Biological Sciences
- Vol. 2 (02), 60-70
- https://doi.org/10.47419/bjbabs.v2i02.52
Abstract
Cardiovascular diseases (CVD) represent a major cause of mortality and morbidity worldwide. To date, many physicians still requesting traditional lipid profile tests (TG, TC, HDL-C, and LDL-C) to confirm the clinical diagnosis related to CVD. However, using these tests may be inadequate for the prediction of CVD risk, especially in intermediate risk. For better clinical practice, laboratory diagnostic alternatives should constantly be evaluated and developed by physicians and laboratory scientists. In this review, we sought to focus on the benefits of lipid ratios (CRI-, CRI-II, AIP, AC, and CHOLindex) in supporting clinical diagnosis and how they can be calculated. To attain this aim, a literature search in reputed databases (PubMed and Scopus) was performed and peer-reviewed research articles were included to conduct this review. Short theoretical and practical notes about each index were accordingly included along with calculation formulas. Thus, the current article can assist new researchers and young physicians to review what supports their knowledge in managing early CVDs.Keywords
This publication has 40 references indexed in Scilit:
- European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)European Heart Journal, 2012
- The metabolic syndrome in Africa: Current trendsIndian Journal of Endocrinology and Metabolism, 2012
- Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiographyJournal of Lipid Research, 2011
- “Atherogenic index of plasma” (log10 triglyceride/high-density lipoprotein−cholesterol) predicts high blood pressure, diabetes, and vascular eventsJournal of Clinical Lipidology, 2010
- Lipid Management to Reduce Cardiovascular Risk: A New Strategy Is RequiredCirculation, 2008
- Utility of Non–High-Density Lipoprotein Cholesterol Versus Other Lipoprotein Measures in Detecting Subclinical Atherosclerosis in Young Adults (The Bogalusa Heart Study)The American Journal of Cardiology, 2007
- Coronary Calcification, Coronary Disease Risk Factors, C-Reactive Protein, and Atherosclerotic Cardiovascular Disease Events: The St. Francis Heart StudyJournal of Invasive Cardiology, 2005
- Relationship between Serum Lipoprotein Ratios and Insulin Resistance in ObesityClinical Chemistry, 2004
- Improving Coronary Heart Disease Risk Assessment in Asymptomatic PeopleCirculation, 2001
- Summary estimates of cholesterol used to predict coronary heart disease.Circulation, 1983