Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry
Open Access
- 23 February 2021
- journal article
- research article
- Published by American Society for Microbiology in mBio
- Vol. 12 (1)
- https://doi.org/10.1128/mbio.03141-20
Abstract
Mycobacterium tuberculosis ( Mtb ) invades alveolar macrophages through phagocytosis to establish infection and cause disease. The molecular mechanisms underlying Mtb entry are still poorly understood.Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (SFB944-P14, HO3539/1-1)
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases (1R01AI141549-01A1)
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