A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib

Abstract
The irreversible Bruton tyrosine kinase (BTK) inhibitor ibrutinib has changed the therapeutic landscape of patients affected by chronic lymphocytic leukemia (CLL), leading to high clinical response...
Funding Information
  • Associazione Italiana per la Ricerca sul Cancro
  • Fondazione Cariplo [
  • Fondazione Umberto Veronesi