Background Studies have shown that low serum magnesium levels and microalbuminuria are associated with type 2 diabetes mellitus patients, which are the known predictors of risk for cardiovascular disease. The chief objective of this study is to evaluate the relationship between serum magnesium level with glycated hemoglobin and urine albumin levels in clinically uncomplicated type 2 diabetes mellitus patients. Methodology During this study, 35 were type 2 diabetes mellitus patients and 20 normal healthy subjects were age and sex matched, were evaluated for serum magnesium, urine albumin, glycated hemoglobin, fasting blood sugar, blood urea and serum creatinine levels. Results In 37% of the diabetic patients, magnesium concentrations were below the normal reference value. Micro albuminuria was seen in 60% of the diabetic cases. Serum magnesium level was correlated with glycemic control, as measured by HbA1c. Conclusion The findings of this study indicate that lower serum magnesium concentrations and microalbuminuria are common in type 2 diabetics. Low serum magnesium level was attributed to poor glycemic control in diabetics. Serum magnesium levels did not correlate with microalbuminuria among diabetics. How to cite this article Sushma S, Devi MSK, Naveen S. The Study of Relationship between Serum Magnesium and Glycated Hemoglobin in Clinically Uncomplicated Type 2 Diabetes Mellitus Patients. J Health Sci Res 2015;6(1):14.