The research featured various means of psychological and pedagogical support of college students from foster families aimed at developing their socio-psychological adaptation. The authors identified the key characteristics of the socio-psychological adaptability of underage orphan students. Students that spent less than a year in foster families combined adaptation with behavioral regulation and demonstrated communicative potential, long-term goals, interest in life, and a sense of purpose. They were active, strong, and satisfied with their self-realization and self-image. Their maladaptation disorders, as well as asthenic and psychotic reactions, were minimal. The key characteristics of the socio-psychological adaptation of minor students from foster families were manifested in the inverse relationship of maladaptation with the life process, locus of self-control, behavioral regulation, communicative potential, moral norms and maladaptation disorders. In underage students from orphanages, adaptation was associated with the locus of control – life, behavioral regulation and minimized asthenic reactions. The authors designed and tested a set of means of psychological and pedagogical support that improve the socio-psychological adaptation of students from foster families. The experiment demonstrated a positive dynamics in the level of adaptation, emotional comfort, sense of purpose, internality and personal adaptive potential, as well as a decrease in the level of maladaptation.