Knockout of the radical scavenger α1-microglobulin in mice results in defective bikunin synthesis, endoplasmic reticulum stress and increased body weight
- 1 January 2021
- journal article
- research article
- Published by Elsevier BV in Free Radical Biology & Medicine
- Vol. 162, 160-170
- https://doi.org/10.1016/j.freeradbiomed.2020.02.019
Abstract
No abstract availableKeywords
Funding Information
- Stiftelsen för Strategisk Forskning
- Kungliga Fysiografiska Sällskapet i Lund
- Vetenskapsrådet
This publication has 48 references indexed in Scilit:
- Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alphaNucleic Acids Research, 2012
- Insertion of Heme b into the Structure of the Cys34‐Carbamidomethylated Human Lipocalin α1‐Microglobulin: Formation of a [(Heme)2(α1‐Microglobulin)]3 ComplexChemBioChem, 2012
- The Unfolded Protein Response: From Stress Pathway to Homeostatic RegulationScience, 2011
- Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose IntoleranceOnline Journal of Public Health Informatics, 2010
- Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein responseThe Journal of cell biology, 2009
- Reduced body weight is a common effect of gene knockout in miceBMC Genomic Data, 2008
- Redox properties of the lipocalin α1-microglobulin: Reduction of cytochrome c, hemoglobin, and free ironFree Radical Biology & Medicine, 2005
- XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription FactorCell, 2001
- The crystal structure of bikunin from the inter-α-inhibitor complex: A serine protease inhibitor with two kunitz domainsJournal of Molecular Biology, 1998
- Rat β2-microglobulin isolation, properties and relation to β2-microglobulins from other speciesMolecular Immunology, 1979